PIPA5116354
MELK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116354-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5116354 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MELK
Classification
Polyclonal
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q61846
Gene Symbols
MELK
Immunogen
KLH conjugated synthetic peptide between 381-415 amino acids from the Central region of Mouse Melk
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
MELK
Gene Alias
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17279
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MELK is a serine/threonione kinase which is related to the AMPK family that has been linked to the cell cycle
- MELK has also been shown to be overexpressed in cancer and has been identified has a potential target for cancer therapeutics
- MELK has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622
- Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1
- Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis
- Plays a key role in cell proliferation and carcinogenesis
- Required for proliferation of embryonic and postnatal multipotent neural progenitors
- Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14
- Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus
- May also play a role in primitive hematopoiesis.
Compare Similar Items
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Antigen: MELK
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q61846
Gene Symbols: MELK
Immunogen: KLH conjugated synthetic peptide between 381-415 amino acids from the Central region of Mouse Melk
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: MELK
Gene Alias: AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17279
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MELK
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q61846
Gene Symbols:
MELK
Immunogen:
KLH conjugated synthetic peptide between 381-415 amino acids from the Central region of Mouse Melk
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
MELK
Gene Alias:
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17279
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SCXA
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q64124
Gene Symbols: SCX
Immunogen: KLH conjugated synthetic peptide between 172-205 amino acids from the C-terminal region of Mouse Scx
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: SCX
Gene Alias: basic helix-loop-helix transcription factor scleraxis; BB114693; Bhlha41; BHLHA48; class A basic helix-loop-helix protein 41; Class A basic helix-loop-helix protein 48; class II bHLH protein scleraxis; Scl; scleraxis; scleraxis basic helix-loop-helix transcription factor; scleraxis bHLH transcription factor; scleraxis homolog A; scleraxis homolog B; SCX; SCXA; SCXB
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20289
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SCXA
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q64124
Gene Symbols:
SCX
Immunogen:
KLH conjugated synthetic peptide between 172-205 amino acids from the C-terminal region of Mouse Scx
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
SCX
Gene Alias:
basic helix-loop-helix transcription factor scleraxis; BB114693; Bhlha41; BHLHA48; class A basic helix-loop-helix protein 41; Class A basic helix-loop-helix protein 48; class II bHLH protein scleraxis; Scl; scleraxis; scleraxis basic helix-loop-helix transcription factor; scleraxis bHLH transcription factor; scleraxis homolog A; scleraxis homolog B; SCX; SCXA; SCXB
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20289
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MTM1
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: MTM1
Immunogen: KLH conjugated synthetic peptide between 451-485 amino acids from the region of DANRE mtm1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: MTM1
Gene Alias: AF073996; CG2; CNM; fb19c01; hypothetical protein LOC560881; im:6903724; mKIAA4176; Mtm; MTM1; MTMX; myotubularin; myotubularin 1; Myotubularin-like protein; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase; wu:fb19c01; X-linked myotubular myopathy gene 1; XLMTM; zgc:123266
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 560881
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MTM1
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
0
Gene Symbols:
MTM1
Immunogen:
KLH conjugated synthetic peptide between 451-485 amino acids from the region of DANRE mtm1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
MTM1
Gene Alias:
AF073996; CG2; CNM; fb19c01; hypothetical protein LOC560881; im:6903724; mKIAA4176; Mtm; MTM1; MTMX; myotubularin; myotubularin 1; Myotubularin-like protein; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase; wu:fb19c01; X-linked myotubular myopathy gene 1; XLMTM; zgc:123266
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
560881
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NFE4
Classification: Polyclonal
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q86UQ8
Gene Symbols: NFE4
Immunogen: KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: NFE4
Gene Alias: fetal globin activator NF-E4; gamma-globin gene activator; NFE4; NF-E4; nuclear factor, erythroid 4; transcription factor NF-E4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 58160
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NFE4
Classification:
Polyclonal
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q86UQ8
Gene Symbols:
NFE4
Immunogen:
KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
NFE4
Gene Alias:
fetal globin activator NF-E4; gamma-globin gene activator; NFE4; NF-E4; nuclear factor, erythroid 4; transcription factor NF-E4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
58160
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid