PIPA5116499

SOCS3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5116499-Each-of-1 In Stock ₹ 44,705.10

PIPA5116499 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SOCS3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Socs3

Gene Alias

ATOD4; CIS3; CIS-3; Cish3; cytokine inducible SH2-containing protein 3; cytokine-inducible SH2 protein 3; E2a-Pbx1 target gene in fibroblasts 10; Ef10; EF-10; MGC71791; Protein EF-10; Socs3; Socs-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; Suppressor of cytokine signaling 3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12702, 89829, 9021

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.39 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O14543, O35718, O88583

Gene Symbols

Socs3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 101-225 of human SOCS3 (NP_0039463)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse lung, Mouse spleen Immunogen sequence: SFSLQSDPRS TQPVPRFDCV LKLVHHYMPP PGAPSFPSPP TEPSSEVPEQ PSAQPLPGSP PRRAYYIYSG GEKIPLVLSR PLSSNVATLQ HLCRKTVNGH LDSYEKVTQL PGPIREFLDQ YDAPL Accumulating evidence demonstrates that cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules Termed SOCS (Suppressor of Cytokine Signaling)
  • To date, there are eight members of SOCS family have been recognized, they are SOCS-1, 2, 3, 4, 5, 6, 7 and CIS
  • Structurally the SOCS proteins are composed of an N-terminal region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C-terminal motif that we have called the SOCS box
  • The SOCS proteins appear to form part of a classical negative feed back loop that regulates cytokine signal transduction via a STAT-induced transcriptional mechanism
  • Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5116499

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Antigen:
SOCS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Socs3

Gene Alias:
ATOD4; CIS3; CIS-3; Cish3; cytokine inducible SH2-containing protein 3; cytokine-inducible SH2 protein 3; E2a-Pbx1 target gene in fibroblasts 10; Ef10; EF-10; MGC71791; Protein EF-10; Socs3; Socs-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; Suppressor of cytokine signaling 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12702, 89829, 9021

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O14543, O35718, O88583

Gene Symbols:
Socs3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 101-225 of human SOCS3 (NP_0039463)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116500

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Antigen:
NeuN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBFOX3

Gene Alias:
D11Bwg0517e; FLJ56884; FLJ58356; fox 1 homolog (C. elegans) 3; fox1 homolog C; Fox-1 homolog C; FOX3; FOX-3; FOX3NeuN; hexaribonucleotide binding protein 3; hexaribonucleotide binding protein 3 (HRNBP3); Hexaribonucleotide-binding protein 3; Hrnbp3; NEUN; NeuN antigen; Neuna60; neuronal nuclear antigen A60; neuronal nuclei; Neuronal nuclei antigen; RBFOX3; RFOX3; RGD1560070; RNA binding fox-1 homolog 3; RNA binding protein; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; RNA binding protein, fox-1 homolog 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
146713, 287847, 52897

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
A6NFN3, Q8BIF2

Gene Symbols:
RBFOX3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of NeuN (NP_0010760441)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5116501

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Antigen:
NEK8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEK8

Gene Alias:
4632401F23Rik; b2b1449Clo; JCK; juvenile cystic kidney; NEK 8; NEK12A; Nek8; nephrocystin 9; never in mitosis A-related kinase 8; NIMA (never in mitosis gene a)- related kinase 8; NIMA (never in mitosis gene a)-related expressed kinase 8; NIMA related kinase 8; NIMA-family kinase NEK8; NIMA-related expressed kinase 8; NIMA-related kinase 12a; NIMA-related kinase 8; nima-related protein kinase 12a; NimA-related protein kinase 8; NPHP9; RHPD2; Serine/threonine-protein kinase Nek8; serine/thrionine-protein kinase NEK8

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140859, 284086, 287473

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
D3ZGQ5, Q86SG6, Q91ZR4

Gene Symbols:
NEK8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-390 of human NEK8 (NP_8354641)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116502

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Antigen:
DJ-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Park7

Gene Alias:
CAP1; Contraception-associated protein 1; CTA-215D11.1; dj1; DJ-1; DJ-1 protein; early onset 7; epididymis secretory sperm binding protein Li 67p; fertility protein SP22; FLJ27376; FLJ34360; FLJ92274; HEL-S-67p; hypothetical protein LOC449674; maillard deglycase; Oncogene DJ1; OTTHUMP00000001350; OTTHUMP00000001351; PARK7; PARK7 GENE; PARK7/DJ1; parkinson disease (autosomal recessive, early onset) 7; Parkinson disease 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; Parkinson disease protein 7 homolog; protein/nucleic acid deglycase DJ-1; parkinson protein 7; Parkinsonism associated deglycase; parkinsonism-associated deglycase; Protein CAP1; protein deglycase DJ-1; protein deglycase DJ-1zDJ-1; Protein DJ-1; protein DJ-1-like protein; protein DJ-1zDJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit; SP22; zDJ-1; zgc:103725

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11315, 57320

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.74 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q99497, Q99LX0

Gene Symbols:
Park7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-189 of human DJ-1/PARK7 (NP_0091932)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG