PIPA5116703

Factor XII Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5116703-Each-of-1 In Stock ₹ 44,705.10

PIPA5116703 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Factor XII

Classification

Polyclonal

Conjugate

Unconjugated

Gene

F12

Gene Alias

beta-factor XIIa part 1; Beta-factor XIIa part 2; coagulation factor XII; coagulation factor XII (Hageman factor); coagulation factor XIIa heavy chain; Coagulation factor XIIa light chain; F12; F13; Factor 12; factor XII; Factor12; FXII; HAE3; HAEX; HAF; hageman factor

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2161, 306761, 58992

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.43 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

D3ZTE0, P00748, Q80YC5

Gene Symbols

F12

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 336-615 of human F12 (NP_0004962)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: HepG2, MCF7, Mouse liver Immunogen sequence: QTPGALPAKR EQPPSLTRNG PLSCGQRLRK SLSSMTRVVG GLVALRGAHP YIAALYWGHS FCAGSLIAPC WVLTAAHCLQ DRPAPEDLTV VLGQERRNHS CEPCQTLAVR SYRLHEAFSP VSYQHDLALL RLQEDADGSC ALLSPYVQPV CLPSGAARPS ETTLCQVAGW GHQFEGAEEY ASFLQEAQVP FLSLERCSAP DVHGSSILPG MLCAGFLEGG TDACQGDSGG PLVCEDQAAE RRLTLQGIIS WGSGCGDRNK PGVYTDVAYY LAWIREHTVS This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain
  • The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain
  • On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain
  • Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa
  • The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin
  • It activates coagulation factors VII and XI
  • Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5116703

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Antigen:
Factor XII

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
F12

Gene Alias:
beta-factor XIIa part 1; Beta-factor XIIa part 2; coagulation factor XII; coagulation factor XII (Hageman factor); coagulation factor XIIa heavy chain; Coagulation factor XIIa light chain; F12; F13; Factor 12; factor XII; Factor12; FXII; HAE3; HAEX; HAF; hageman factor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2161, 306761, 58992

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.43 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
D3ZTE0, P00748, Q80YC5

Gene Symbols:
F12

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 336-615 of human F12 (NP_0004962)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116704

--


Antigen:
MMP13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP13

Gene Alias:
cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171052, 17386, 4322

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P23097, P33435, P45452

Gene Symbols:
MMP13

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 104-272 of human MMP13 (NP_0024181)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116705

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Antigen:
NDUFB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDUFB1

Gene Alias:
CI-MNLL; CI-SGDH; complex I MNLL subunit; complex I-MNLL; MNLL; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; NADH:ubiquinone oxidoreductase subunit B1; NADH-ubiquinone oxidoreductase MNLL subunit; Ndufb1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110324555, 4707

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O75438, P0DN34

Gene Symbols:
NDUFB1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human NDUFB1 (NP_0045362)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116707

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Antigen:
PRIM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRIM1

Gene Alias:
AI324982; DNA primase 1; DNA primase 49 kDa subunit; DNA primase small subunit; DNA primase subunit 48; DNA primase, p49 subunit; MGC12308; p49; PRI1; PRIM1; primase (DNA) subunit 1; primase p49 subunit; primase polypeptide 1, 49kDa; primase, DNA, polypeptide 1; primase, DNA, polypeptide 1 (49kDa)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19075, 5557

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P20664, P49642

Gene Symbols:
PRIM1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-420 of human PRIM1 (NP_0009371)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG