PIPA511671

CD45 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511671-Each-of-1 In Stock ₹ 47,015.22

PIPA511671 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

CD45

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

KLH conjugated synthetic peptide between 1245-1275 amino acids from the C-terminal region of human CD45

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5114641

--

Img

Thermo Scientific

PIPA5114642

--

Img

Thermo Scientific

PIPA5116645

--

Img

Thermo Scientific

PIPA511454

--

Img

Thermo Scientific

PIPA511453

--

Img

Thermo Scientific

PIPA5117053

--

Img

Thermo Scientific

PIPA5117114

--

Img

Thermo Scientific

PIPA5114369

--

Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA511671

--


Antigen:
CD45

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
KLH conjugated synthetic peptide between 1245-1275 amino acids from the C-terminal region of human CD45

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116710

--


Antigen:
TOP3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Top3a

Gene Alias:
DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; Top IIIa; TOP3; TOP3A; topo III-alpha; topoisomerase (DNA) 3 alpha; topoisomerase (DNA) III alpha; topoisomerase 3 alpha; ZGRF7; zinc finger, GRF-type containing 7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21975

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.46 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O70157

Gene Symbols:
Top3a

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOP3A (XP_0115223031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116713

--


Antigen:
SLMAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slmap

Gene Alias:
D330001L02Rik; KIAA1601; mKIAA1601; sarcolemma associated protein; sarcolemmal membrane-associated protein; Sarcolemmal-associated protein; Slap; Slmap; UNQ1847/PRO3577

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
290533, 7871, 83997

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P0C219, Q14BN4, Q3URD3

Gene Symbols:
Slmap

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_0090902)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116714

--


Antigen:
SLC25A16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC25A16

Gene Alias:
3110021G18Rik; D10S105E; GDA; GDC; Graves disease autoantigen; Graves disease carrier protein; Graves disease carrier protein from bovine heart mitochondria; graves disease carrier protein homolog; HGT.1; hML7; MGC39851; mitochondrial carrier; human : Graves disease autoantigen; mitochondrial solute carrier protein homolog; ML7; SLC25A16; solute carrier family 25 (mitochondrial carrier), member 16; solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16; solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16; solute carrier family 25 member 16; solute carrier family 25, member 16; Unknown (protein for MGC:77742); wu:fc33c08; zgc:56187; zgc:77742

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361836, 73132, 8034

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.71 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P16260, P16261, Q8C0K5

Gene Symbols:
SLC25A16

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC25A16 (NP_6899201)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG