PIPA5116721
PUMA alpha Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116721-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5116721 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PUMA alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BBC3
Gene Alias
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
170770, 27113, 317673
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.39 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q80ZG6, Q96PG8, Q99ML1, Q9BXH1
Gene Symbols
BBC3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-131 of human PUMA (NP_0011207131)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549, LO2, HepG2, K562 Immunogen sequence: PGALAGGPTQ AAPGVRGEEE QWAREIGAQL RRMADDLNAQ YERRRQEEQQ RHRPSPWRVL YNLIMGLLPL PRGHRAPEME PN PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
- The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
- PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
- PUMA may be a direct mediator of p53-induced apoptosis
- Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.
Compare Similar Items
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Antigen: PUMA alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BBC3
Gene Alias: BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 170770, 27113, 317673
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.39 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q80ZG6, Q96PG8, Q99ML1, Q9BXH1
Gene Symbols: BBC3
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-131 of human PUMA (NP_0011207131)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PUMA alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BBC3
Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
170770, 27113, 317673
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.39 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q80ZG6, Q96PG8, Q99ML1, Q9BXH1
Gene Symbols:
BBC3
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-131 of human PUMA (NP_0011207131)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CPSF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cpsf1
Gene Alias: cleavage and polyadenylation specific factor 1; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF1; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29894, 94230
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.65 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q10570, Q9EPU4
Gene Symbols: Cpsf1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_0374232)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CPSF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cpsf1
Gene Alias:
cleavage and polyadenylation specific factor 1; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF1; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29894, 94230
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.65 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q10570, Q9EPU4
Gene Symbols:
Cpsf1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_0374232)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TMX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMX2
Gene Alias: 2310042M24Rik; AA589631; Cell proliferation-inducing gene 26 protein; CGI-31; growth-inhibiting gene 11; My009; PDIA12; PIG26; protein disulfide isomerase family A, member 12; PSEC0045; thioredoxin domain containing 14; thioredoxin domain-containing protein 14; thioredoxin related transmembrane protein 2; thioredoxin-related transmembrane protein 2; thioredoxin-related transmembrane protein-like protein; TMX2; TXNDC14; Unknown (protein for MGC:134152); UNQ237/PRO270
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 295701, 51075, 66958
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.67 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q5XIK2, Q9D710, Q9Y320
Gene Symbols: TMX2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 128-296 of human TMX2 (NP_0570431)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TMX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMX2
Gene Alias:
2310042M24Rik; AA589631; Cell proliferation-inducing gene 26 protein; CGI-31; growth-inhibiting gene 11; My009; PDIA12; PIG26; protein disulfide isomerase family A, member 12; PSEC0045; thioredoxin domain containing 14; thioredoxin domain-containing protein 14; thioredoxin related transmembrane protein 2; thioredoxin-related transmembrane protein 2; thioredoxin-related transmembrane protein-like protein; TMX2; TXNDC14; Unknown (protein for MGC:134152); UNQ237/PRO270
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
295701, 51075, 66958
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.67 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q5XIK2, Q9D710, Q9Y320
Gene Symbols:
TMX2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 128-296 of human TMX2 (NP_0570431)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: REEP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: REEP2
Gene Alias: C2orf19; C5orf19; LOC532432 protein; LOC682105; receptor accessory protein 2; receptor expression-enhancing protein 2; Reep2; SGC32445; SPG72; Yip2d
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 225362, 682105
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.53 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q8VCD6
Gene Symbols: REEP2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 93-252 of human REEP2 (NP_0576902)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
REEP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
REEP2
Gene Alias:
C2orf19; C5orf19; LOC532432 protein; LOC682105; receptor accessory protein 2; receptor expression-enhancing protein 2; Reep2; SGC32445; SPG72; Yip2d
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
225362, 682105
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q8VCD6
Gene Symbols:
REEP2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 93-252 of human REEP2 (NP_0576902)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG