PIPA5116815

GSDMD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116815-Each-of-1 In Stock ₹ 46,758.54

PIPA5116815 - Each of 1

₹ 46,758.54

In Stock

Quantity

1

Base Price: ₹ 46,758.54

GST (18%): ₹ 8,416.537

Total Price: ₹ 55,175.077

Antigen

GSDMD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSDMD

Gene Alias

1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

315084, 69146, 79792

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1.65 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

P57764, Q9D8T2

Gene Symbols

GSDMD

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 154-252 of human GSDMD (NP_079012.3).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: PC-3, THP-1, Jurkat Immunogen sequence: GDNVYVVTEV LQTQKEVEVT RTHKREGSGR FSLPGATCLQ GEGQGHLSQK KTVTIPSGST LAFRVAQLVI DSDLDVLLFP DKKQRTFQPP ATGHKRSTS GSDMD (gasdermin-D) promotes pyroptosis in response to microbial infection and danger signals
  • It is produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as, non-canonical (such as cytosolic LPS) inflammasome activators
  • After cleavage, GSDMD moves to the plasma membrane where it strongly binds to inner leaflet lipids including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-biphosphate, phosphatidylinositol (3,4,5)-biphosphate, phosphatidic acid, and phosphatidylserine
  • GSDMD also exhibits bactericidal activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5116815

--


Antigen:
GSDMD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSDMD

Gene Alias:
1810036L03Rik; AW558049; DF5L; Dfna5l; FKSG10; gasdermin D; gasdermin domain containing 1; gasdermin domain-containing protein 1; Gasdermin-D; Gasdermin-D, C-terminal; Gasdermin-D, N-terminal; GSDMD; GSDMDC1; GSDMD-CT; GSDMD-NT; M2-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315084, 69146, 79792

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.65 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P57764, Q9D8T2

Gene Symbols:
GSDMD

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 154-252 of human GSDMD (NP_079012.3).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5116816

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Antigen:
Tri-Methyl Lysine

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Trimethyllysine

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.52 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthetic peptide corresponding to a sequence containing trimethylated K

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chemical, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5116817

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Antigen:
Mono-Methyl Lysine

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
monomethyl lysine

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthetic peptide corresponding to a sequence containing monomethylated K

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chemical, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5116818

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Antigen:
Di-Methyl Lysine

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Dimethyllysine

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthetic peptide corresponding to a sequence containing dimethylated K

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chemical, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG