PIPA5116888

ULK1/ULK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116888-Each-of-1 In Stock ₹ 44,705.10

PIPA5116888 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ULK1/ULK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ULK1

Gene Alias

ATG1; ATG1 autophagy related 1 homolog; ATG1A; ATG1B; Autophagy-related protein 1 homolog; hATG1; KIAA0623; KIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase ULK2; ULK1; ULK2; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like autophagy activating kinase 2; Unc51.1; Unc51.2; Unc-51-like kinase 1; Unc-51-like kinase 2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8408, 9706

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O75385, Q8IYT8

Gene Symbols

ULK1, ULK2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human ULK1/ULK2 (NP_0035561)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5117270

--

Img

Thermo Scientific

PIPA5116716

--

Img

Thermo Scientific

PIPA5117205

--

Img

Thermo Scientific

PIPA5116560

--

Img

Thermo Scientific

PIPA5117296

--

Img

Thermo Scientific

PIPA5116800

--

Img

Thermo Scientific

PIPA5116858

--

Img

Thermo Scientific

PIPA5116780

--

Description

  • Positive Samples: RD, SH-SY5Y, HepG2 Immunogen sequence: MEPGRGGTET VGKFEFSRKD LIGHGAFAVV FKGRHREKHD LEVAVKCINK KNLAKSQTLL GKEIKILKEL KHENIVALYD FQEMANSVYL VMEYCNGGDL ADYLHAMRTL SEDTIRLFLQ QIAGAMRLLH SKGIIHRDLK PQNILLSNPA GRRANPNSIR VKIADFGFAR YLQSNMMAAT LCGSPMYMAP EVIMSQHYDG KADLWSIGTI VYQCLTGKAP FQASSPQDLR LFYEKNKTLV PTIPRETSAP LRQLLLALLQ RNHKDRMDFD EFFHHPFLDA SPS Mammalian ULK1 (unc-51 like kinase 1) and ULK2, Caenorhabditis elegans UNC-51, and Drosophila melanogaster Atg1 are serine/threonine kinases that regulate flux through the autophagy pathway in response to various types of cellular stress.ULK1 and ULK2 all have different tissue-specific expressions partially contributing to diverse and ULK-specific interaction networks in various tissues.ULK1 (or its close family member ULK2) interacts with several other proteins to form a large complex that is required for the formation of an autophagosome
  • The other proteins that complex with ULK1/ULK2 include ATG13, ATG101, and RB1CC1 (FIP200/ATG17).AMPK, activated during low nutrient conditions, directly phophorylates ULK1 at multiple sites including Ser317, Ser555, and Ser777
  • Conversely, mTOR, which is a regulator of cell growth and is an inhibitor of autophagy, phosphorylates ULK1 at Ser757 and disrupts the interaction between ULK1 and AMPK.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5116888

--


Antigen:
ULK1/ULK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ULK1

Gene Alias:
ATG1; ATG1 autophagy related 1 homolog; ATG1A; ATG1B; Autophagy-related protein 1 homolog; hATG1; KIAA0623; KIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase ULK2; ULK1; ULK2; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like autophagy activating kinase 2; Unc51.1; Unc51.2; Unc-51-like kinase 1; Unc-51-like kinase 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8408, 9706

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O75385, Q8IYT8

Gene Symbols:
ULK1, ULK2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human ULK1/ULK2 (NP_0035561)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116891

--


Antigen:
SUPT16H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT16H

Gene Alias:
Cdc68; Chromatin-specific transcription elongation factor 140 kDa subunit; chromatin-specific transcription elongation factor large subunit; DNA unwinding factor 140 kDa subunit; DUF140; facilitates chromatin remodeling 140 kDa subunit; facilitates chromatin transcription complex subunit spt16; FACT; FACT 140 kDa subunit; FACT complex subunit SPT16; FACT complex subunit SPT16-like protein; FACT140; Factp140; FLJ10857; FLJ14010; FLJ34357; fq44d08; HGNC:11465; hSPT16; SPT16; SPT16 homolog, facilitates chromatin remodeling subunit; SPT16/CDC68; suppressor of Ty 16; suppressor of Ty 16 homolog; suppressor of Ty 16 homolog (S. cerevisiae); Supt16; supt16h; wu:fq44d08; zgc:194708; zgc:194732

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11198, 114741, 305851

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.54 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q920B9, Q9Y5B9

Gene Symbols:
Supt16, SUPT16H

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-695 of human SUPT16H (SPT16) (NP_0091231)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116892

--


Antigen:
VAMP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Vamp7

Gene Alias:
Sybl1; synaptobrevin-like 1; synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP; tetanus-insensitive VAMP; TIVAMP; Ti-VAMP; vamp; Vamp7; VAMP-7; vesicle associated membrane protein 7; vesicle-associated membrane protein 7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20955, 6845, 85491

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P51809, P70280, Q9JHW5

Gene Symbols:
Vamp7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 11-70 of human VAMP7 (P51809)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116893

--


Antigen:
SP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SP7

Gene Alias:
6430578P22Rik; C22; MGC126598; OI11; OI12; osterix; OSX; Sp7; Sp7 transcription factor; Sp7 transcription factor 7; trans-acting transcription factor 7; transcription factor Sp7; Zinc finger protein osterix

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121340, 170574, 300260

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
Q8TDD2, Q8VI67

Gene Symbols:
SP7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 333-376 of human SP7 (NP_0011669381)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG