PIPA5116941
SARS-CoV-2 NSP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116941-Each-of-1 | In Stock | ₹ 45,047.34 |
PIPA5116941 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,047.34
GST (18%): ₹ 8,108.521
Total Price: ₹ 53,155.861
Antigen
SARS-CoV-2 NSP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of coronavirus NSP1 (YP_0097426081)
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1.48 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T Immunogen sequence: MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG Inhibits host translation by interacting with the 40S ribosomal subunit (PubMed:32680882)
- Nsp1 C terminus binds to and obstructs ribosomal mRNA entry tunnel (PubMed:32680882)
- Thereby inhibits antiviral response triggered by innate immunity or interferons (PubMed:32680882)
- The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation
- Viral mRNAs are not susceptible to nsp1-mediated endonucleolytic RNA cleavage thanks to the presence of a 5'-end leader sequence and are therefore protected from degradation
- By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response.
Compare Similar Items
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Antigen: SARS-CoV-2 NSP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of coronavirus NSP1 (YP_0097426081)
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1.48 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS-CoV-2 NSP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 Nsp1; COVID-19 Nsp1; SARS-CoV-2 Nonstructural Protein 1; SARS-CoV2 NSP1; SARS-COV-2 NSP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of coronavirus NSP1 (YP_0097426081)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1.48 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: hnRNP A3
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: 2410013L13Rik; 2610209F03Rik; 2610510D13Rik; D10S102; FBRNP; Heterogeneous nuclear ribonucleoprotein A3; hnRNP A3; Hnrnpa3; HNRPA3; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A3
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HNRNPA3 (NP_0013171781)
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.47 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
hnRNP A3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
2410013L13Rik; 2610209F03Rik; 2610510D13Rik; D10S102; FBRNP; Heterogeneous nuclear ribonucleoprotein A3; hnRNP A3; Hnrnpa3; HNRPA3; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A3
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HNRNPA3 (NP_0013171781)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.47 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SARS-CoV-2 ORF3a
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of coronavirus ORF3A (YP_0097243911)
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
SARS-CoV-2 ORF3a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of coronavirus ORF3A (YP_0097243911)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: ASB17
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: 4933436O18Rik; ankyrin repeat and SOCS box containing 17; ankyrin repeat and SOCS box containing protein 17; ankyrin repeat and SOCS box protein 17; ankyrin repeat and SOCS box-containing 17; ankyrin repeat and SOCS box-containing protein 17; Asb17; ASB-17
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 78-177 of mouse ASB17 (NP_0800342)
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.656 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASB17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
4933436O18Rik; ankyrin repeat and SOCS box containing 17; ankyrin repeat and SOCS box containing protein 17; ankyrin repeat and SOCS box protein 17; ankyrin repeat and SOCS box-containing 17; ankyrin repeat and SOCS box-containing protein 17; Asb17; ASB-17
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 78-177 of mouse ASB17 (NP_0800342)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.656 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG