PIPA5116972
APE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116972-Each-of-1 | In Stock | ₹ 45,560.70 |
PIPA5116972 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,560.70
GST (18%): ₹ 8,200.926
Total Price: ₹ 53,761.626
Antigen
APE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APEX1
Gene Alias
AP endonuclease 1; AP endonuclease class I; AP lyase; Ape; APE1; APEN; Apex; APEX nuclease; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease 1; Apex1; apurinic/a; Apurinic/apy; apurinic/apyrimidinic (abasic) endonuclease; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endonuclease; apurinic/apyrimidinic endonuclease 1; Apurinic-apyrimidinic endonuclease 1; APX; BAP 1; BAP1; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; HAP1; protein REF-1; redox factor 1; redox factor-1; REF1; REF-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
328
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
2.293 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P27695
Gene Symbols
APEX1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HeLa, HepG2 Immunogen sequence: MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS APSDKEGYSG VGLLSRQCPL KVSYGIGDEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI RSKALGSDHC PITLYLAL Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
- APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
- The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
- APE is differentially expressed during development and in different tissues
- This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
- Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
- Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some malignant tissue relative to normal tissue
- Decreases in APE expression have been associated with the induction of cellular apoptosis.
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Antigen: APE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APEX1
Gene Alias: AP endonuclease 1; AP endonuclease class I; AP lyase; Ape; APE1; APEN; Apex; APEX nuclease; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease 1; Apex1; apurinic/a; Apurinic/apy; apurinic/apyrimidinic (abasic) endonuclease; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endonuclease; apurinic/apyrimidinic endonuclease 1; Apurinic-apyrimidinic endonuclease 1; APX; BAP 1; BAP1; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; HAP1; protein REF-1; redox factor 1; redox factor-1; REF1; REF-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 328
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 2.293 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P27695
Gene Symbols: APEX1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APEX1
Gene Alias:
AP endonuclease 1; AP endonuclease class I; AP lyase; Ape; APE1; APEN; Apex; APEX nuclease; APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease 1; Apex1; apurinic/a; Apurinic/apy; apurinic/apyrimidinic (abasic) endonuclease; apurinic/apyrimidinic endodeoxyribonuclease 1; apurinic/apyrimidinic endonuclease; apurinic/apyrimidinic endonuclease 1; Apurinic-apyrimidinic endonuclease 1; APX; BAP 1; BAP1; deoxyribonuclease (apurinic or apyrimidinic); DNA-(apurinic or apyrimidinic site) endonuclease; DNA-(apurinic or apyrimidinic site) lyase; DNA-(apurinic or apyrimidinic site) lyase, mitochondrial; HAP1; protein REF-1; redox factor 1; redox factor-1; REF1; REF-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
328
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
2.293 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P27695
Gene Symbols:
APEX1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MAT1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAT1A
Gene Alias: AdoMet; AdoMet synthase 1; adoMet synthetase 1; AI046368; Ams; Ams1; Cartilage matrix protein; CMP; CRTM; MAT; MAT 1; Mat1a; MATA1; MAT-I/III; MATN1; matrilin 1, cartilage matrix protein; Matrilin-1; Methionine adenosyltransferase 1; methionine adenosyltransferase 1A; methionine adenosyltransferase I, alpha; methionine adenosyltransferase I/III; S - adenosylmethionine synthetase; SADE; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthase; S-adenosylmethionine synthetase isoform type-1; SAMS; SAMS1; SAS; similar to S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III); wu:fi35e01; zgc:55442
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11720, 25331, 4143
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.54 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P13444, Q00266, Q91X83
Gene Symbols: MAT1A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_0004201)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MAT1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAT1A
Gene Alias:
AdoMet; AdoMet synthase 1; adoMet synthetase 1; AI046368; Ams; Ams1; Cartilage matrix protein; CMP; CRTM; MAT; MAT 1; Mat1a; MATA1; MAT-I/III; MATN1; matrilin 1, cartilage matrix protein; Matrilin-1; Methionine adenosyltransferase 1; methionine adenosyltransferase 1A; methionine adenosyltransferase I, alpha; methionine adenosyltransferase I/III; S - adenosylmethionine synthetase; SADE; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthase; S-adenosylmethionine synthetase isoform type-1; SAMS; SAMS1; SAS; similar to S-adenosylmethionine synthetase alpha and beta forms (Methionine adenosyltransferase) (AdoMet synthetase) (MAT-I/III); wu:fi35e01; zgc:55442
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11720, 25331, 4143
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.54 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P13444, Q00266, Q91X83
Gene Symbols:
MAT1A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT1A (NP_0004201)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CLEC4D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CLEC4D
Gene Alias: CD368; Clec4d; CLEC6; CLEC-6; CLECSF8; CLECSF8Mpcl; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8; C-type lectin domain family 4 member D; C-type lectin domain family 4, member d; C-type lectin receptor; C-type lectin superfamily member 8; C-type lectin, superfamily member 8; C-type lectin-like receptor 6; macrophage C-type lectin; macrophage-restricted C-type lectin; Mcl; MGC40078; Mpcl; superfamilymember 8
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17474, 338339, 362432
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.49 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q69FH1, Q8WXI8, Q9Z2H6
Gene Symbols: CLEC4D
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_5251262)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CLEC4D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CLEC4D
Gene Alias:
CD368; Clec4d; CLEC6; CLEC-6; CLECSF8; CLECSF8Mpcl; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 8; C-type lectin domain family 4 member D; C-type lectin domain family 4, member d; C-type lectin receptor; C-type lectin superfamily member 8; C-type lectin, superfamily member 8; C-type lectin-like receptor 6; macrophage C-type lectin; macrophage-restricted C-type lectin; Mcl; MGC40078; Mpcl; superfamilymember 8
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17474, 338339, 362432
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.49 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q69FH1, Q8WXI8, Q9Z2H6
Gene Symbols:
CLEC4D
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human CLEC4D (NP_5251262)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: EGR4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EGR4
Gene Alias: AT133; early growth response 4; early growth response protein 4; Early response protein NGFI-C; Egr4; EGR-4; Egr4l1; Nerve growth factor-induced protein C; NGF1-C; Ngfic; NGFI-C; PAT133; zinc-finger transcription factor NGFI-C (early response gene)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13656, 1961, 25129
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.42 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q00911, Q05215, Q9WUF2
Gene Symbols: EGR4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_0019563)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
EGR4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EGR4
Gene Alias:
AT133; early growth response 4; early growth response protein 4; Early response protein NGFI-C; Egr4; EGR-4; Egr4l1; Nerve growth factor-induced protein C; NGF1-C; Ngfic; NGFI-C; PAT133; zinc-finger transcription factor NGFI-C (early response gene)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13656, 1961, 25129
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q00911, Q05215, Q9WUF2
Gene Symbols:
EGR4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_0019563)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG