PIPA5117113
ASAH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117113-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5117113 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ASAH2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Asah2
Gene Alias
acylsphingosine deacylase 2; AI585898; Asah2; BCDase; hCD; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-acylsphingosine amidohydrolase 2; NCDase; N-CDase; Neutral ceramidase; Neutral ceramidase soluble form; neutral/alkaline ceramidase; non-lysosomal ceramidase
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
114104, 54447, 56624
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q91XT9, Q9JHE3, Q9NR71
Gene Symbols
Asah2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 531-780 of human ASAH2 (Q9NR71)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse kidney, Mouse heart Immunogen sequence: SLAITAIPGE FTTMSGRRLR EAVQAEFASH GMQNMTVVIS GLCNVYTHYI TTYEEYQAQR YEAASTIYGP HTLSAYIQLF RNLAKAIATD TVANLSRGPE PPFFKQLIVP LIPSIVDRAP KGRTFGDVLQ PAKPEYRVGE VAEVIFVGAN PKNSVQNQTH QTFLTVEKYE ATSTSWQIVC NDASWETRFY WHKGLLGLSN ATVEWHIPDT AQPGIYRIRY FGHNRKQDIL KPAVILSFEG TSPAFEVVTI Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids
- These ceramidases are classified according to the pH range that supports their optimal activity
- ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5
- ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine
- Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger
- ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart
- Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.
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Antigen: ASAH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Asah2
Gene Alias: acylsphingosine deacylase 2; AI585898; Asah2; BCDase; hCD; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-acylsphingosine amidohydrolase 2; NCDase; N-CDase; Neutral ceramidase; Neutral ceramidase soluble form; neutral/alkaline ceramidase; non-lysosomal ceramidase
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114104, 54447, 56624
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q91XT9, Q9JHE3, Q9NR71
Gene Symbols: Asah2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 531-780 of human ASAH2 (Q9NR71)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASAH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Asah2
Gene Alias:
acylsphingosine deacylase 2; AI585898; Asah2; BCDase; hCD; HNAC1; LCDase; mitochondrial ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-acylsphingosine amidohydrolase 2; NCDase; N-CDase; Neutral ceramidase; Neutral ceramidase soluble form; neutral/alkaline ceramidase; non-lysosomal ceramidase
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114104, 54447, 56624
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q91XT9, Q9JHE3, Q9NR71
Gene Symbols:
Asah2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 531-780 of human ASAH2 (Q9NR71)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: OSGEPL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OSGEPL1
Gene Alias: 2610001M19Rik; AA416452; GCP1; HAMAP-Rule:MF_03179}; N6-L-threonylcarbamoyladenine synthase; OSGEPL1; O-sialoglycoprotein endopeptidase like 1; O-sialoglycoprotein endopeptidase-like 1; O-sialoglycoprotein endopeptidase-like protein 1; O-sialoglycoprotein endopeptidase-like protein 1 {ECO:0000255; probable O-sialoglycoprotein endopeptidase 2; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; putative sialoglycoprotease type 2; Qri7; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1 {ECO:0000255; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1 {ECO:0000255
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 314548, 64172, 72085
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q4V7F3, Q6PEB4, Q9H4B0
Gene Symbols: OSGEPL1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OSGEPL1 (NP_0717482)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
OSGEPL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OSGEPL1
Gene Alias:
2610001M19Rik; AA416452; GCP1; HAMAP-Rule:MF_03179}; N6-L-threonylcarbamoyladenine synthase; OSGEPL1; O-sialoglycoprotein endopeptidase like 1; O-sialoglycoprotein endopeptidase-like 1; O-sialoglycoprotein endopeptidase-like protein 1; O-sialoglycoprotein endopeptidase-like protein 1 {ECO:0000255; probable O-sialoglycoprotein endopeptidase 2; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; putative sialoglycoprotease type 2; Qri7; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgepl1 {ECO:0000255; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; tRNA threonylcarbamoyladenosine biosynthesis protein Osgepl1 {ECO:0000255
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
314548, 64172, 72085
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q4V7F3, Q6PEB4, Q9H4B0
Gene Symbols:
OSGEPL1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human OSGEPL1 (NP_0717482)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LHX4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LHX4
Gene Alias: A330062J17Rik; CPHD4; Gsh4; Gsh-4; Lhx4; LIM homeo box protein 4; LIM homeobox 4; LIM homeobox protein 4; LIM/homeobox protein Lhx4; LXH4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16872, 360858, 89884
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P53776, Q969G2
Gene Symbols: LHX4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 121-390 of human LHX4 (NP_2031291)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LHX4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LHX4
Gene Alias:
A330062J17Rik; CPHD4; Gsh4; Gsh-4; Lhx4; LIM homeo box protein 4; LIM homeobox 4; LIM homeobox protein 4; LIM/homeobox protein Lhx4; LXH4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16872, 360858, 89884
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P53776, Q969G2
Gene Symbols:
LHX4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-390 of human LHX4 (NP_2031291)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD6
Gene Alias: Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 923
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.6 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P30203
Gene Symbols: CD6
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 424-668 of human CD6 (NP_0067163)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD6
Gene Alias:
Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
923
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.6 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P30203
Gene Symbols:
CD6
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 424-668 of human CD6 (NP_0067163)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG