PIPA5117319

HERC5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117319-Each-of-1 In Stock ₹ 44,705.10

PIPA5117319 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HERC5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HERC5

Gene Alias

CEB1; CEBP1; Cyclin-E-binding protein 1; E3 ISG15--protein ligase HERC5; HECT and RLD domain containing E3 ubiquitin protein ligase 5; HECT domain and RCC1-like domain-containing protein 5; hect domain and RLD 5; HERC5; probable E3 ubiquitin-protein ligase HERC5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51191

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.98 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q9UII4

Gene Symbols

HERC5

Immunogen

Recombinant protein encompassing a sequence within the center region of human HERC5. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Centrifuge briefly prior to opening
  • HERC5 (E3 ISG15 - protein ligase HERC5) is a major E3 ligase for ISG15 conjugation
  • It acts a positive regulator of innate antiviral response in cells induced by interferon
  • HERC5 functions as a part of the ISGylation machinery that recognizes target protein in a broad and relatively non-specific manner
  • It catalyzes ISGylation of IRF3 - which results in sustained activation, it attenuates IRF3-PIN1 interaction - which antagonizes IFR3 ubiquitination and degradation, and boosts the antiviral repsonse
  • HERC5 is physically assocated with polyribosomes and broadly modifies newly synthesized proteins in a cotranslational manner.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5117319

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Antigen:
HERC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HERC5

Gene Alias:
CEB1; CEBP1; Cyclin-E-binding protein 1; E3 ISG15--protein ligase HERC5; HECT and RLD domain containing E3 ubiquitin protein ligase 5; HECT domain and RCC1-like domain-containing protein 5; hect domain and RLD 5; HERC5; probable E3 ubiquitin-protein ligase HERC5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51191

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.98 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9UII4

Gene Symbols:
HERC5

Immunogen:
Recombinant protein encompassing a sequence within the center region of human HERC5. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5117320

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Antigen:
MADD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MADD

Gene Alias:
9630059K23Rik; DENN; differentially expressed in normal and neoplastic cells; IG20; Insulinoma glucagonoma clone 20; insulinoma-glucagonoma protein 20; Kiaa0358; Madd; MAP kinase activating death domain; MAP kinase-activating death domain protein; MAP-kinase activating death domain; rab3 GDP/GTP exchange factor; Rab3 GDP/GTP exchange protein; Rab3 GEP; RAB3GEP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228355

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.39 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q80U28

Gene Symbols:
MADD

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5117321

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Antigen:
Phospho-IRE1 alpha (Ser724)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2081

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O75460

Gene Symbols:
ERN1

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human IRE1 alpha (phospho Ser724). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5117322

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Antigen:
Phospho-YAP1 (Ser127)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YAP1

Gene Alias:
65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10413

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P46937

Gene Symbols:
YAP1

Immunogen:
Synthetic peptide corresponding to residues around human YAP1 (phospho Ser127). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG