PIPA5117431
SMCR8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117431-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5117431 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SMCR8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMCR8
Gene Alias
2310076G09Rik; AI642055; D030073L15Rik; FLJ34716; Guanine nucleotide exchange protein SMCR8; RGD1564621; SMCR8; Smith-Magenis syndrome chromosomal region candidate gene 8 protein; Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog; Smith-Magenis syndrome chromosome region, candidate 8; Smith-Magenis syndrome chromosome region, candidate 8 homolog; Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
140775, 497918
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.12 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q8TEV9
Gene Symbols
SMCR8
Immunogen
Recombinant protein encompassing a sequence within the center region of human SMCR8. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Description
- Centrifuge briefly prior to opening
- Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy
- In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation
- The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity
- Acts as a regulator of mTORC1 signaling by promoting phosphorylation of mTORC1 substrates
- In addition to its activity in the cytoplasm within the C9orf72-SMCR8 complex, SMCR8 also localizes in the nucleus, where it associates with chromatin and negatively regulates expression of suppresses ULK1 and WIPI2 genes.
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Antigen: SMCR8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMCR8
Gene Alias: 2310076G09Rik; AI642055; D030073L15Rik; FLJ34716; Guanine nucleotide exchange protein SMCR8; RGD1564621; SMCR8; Smith-Magenis syndrome chromosomal region candidate gene 8 protein; Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog; Smith-Magenis syndrome chromosome region, candidate 8; Smith-Magenis syndrome chromosome region, candidate 8 homolog; Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140775, 497918
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.12 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8TEV9
Gene Symbols: SMCR8
Immunogen: Recombinant protein encompassing a sequence within the center region of human SMCR8. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMCR8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMCR8
Gene Alias:
2310076G09Rik; AI642055; D030073L15Rik; FLJ34716; Guanine nucleotide exchange protein SMCR8; RGD1564621; SMCR8; Smith-Magenis syndrome chromosomal region candidate gene 8 protein; Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog; Smith-Magenis syndrome chromosome region, candidate 8; Smith-Magenis syndrome chromosome region, candidate 8 homolog; Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140775, 497918
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.12 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q8TEV9
Gene Symbols:
SMCR8
Immunogen:
Recombinant protein encompassing a sequence within the center region of human SMCR8. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TOMM22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tomm22
Gene Alias: 1C9-2; 2310047D01; hTom22; Mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; MST065; MSTP065; rTOM22; Tom22; Tomm22; Translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22; translocase of outer mitochondrial membrane 22 homolog; translocase of outer mitochondrial membrane 22 homolog (yeast)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56993
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q9NS69
Gene Symbols: Tomm22
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM22. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TOMM22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tomm22
Gene Alias:
1C9-2; 2310047D01; hTom22; Mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; MST065; MSTP065; rTOM22; Tom22; Tomm22; Translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22; translocase of outer mitochondrial membrane 22 homolog; translocase of outer mitochondrial membrane 22 homolog (yeast)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56993
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q9NS69
Gene Symbols:
Tomm22
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM22. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Lassa Virus Nucleoprotein
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: Lassa mammarenavirus NP; Lassa mammarenavirus Nucleoprotein; Lassa virus NP; Lassa virus Nucleoprotein; LASV NP; LASV Nucleoprotein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.65 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: __
Gene Symbols: __
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Lassa virus Nucleoprotein. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
Lassa Virus Nucleoprotein
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Lassa mammarenavirus NP; Lassa mammarenavirus Nucleoprotein; Lassa virus NP; Lassa virus Nucleoprotein; LASV NP; LASV Nucleoprotein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.65 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Lassa virus Nucleoprotein. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: Lassa Virus Glycoprotein G2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: Lassa mammarenavirus Glycoprotein G2; Lassa virus Glycoprotein G2; LASV Glycoprotein G2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.8 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant protein encompassing a sequence within the center region of Lassa virus Glycoprotein G2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
Lassa Virus Glycoprotein G2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Lassa mammarenavirus Glycoprotein G2; Lassa virus Glycoprotein G2; LASV Glycoprotein G2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.8 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant protein encompassing a sequence within the center region of Lassa virus Glycoprotein G2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG