PIPA5117488

Perforin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117488-Each-of-1 In Stock ₹ 45,560.70

PIPA5117488 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

Perforin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRF1

Gene Alias

Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

18646

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA

Concentration

2 mg/mL

Formulation

10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

P10820

Gene Symbols

PRF1

Immunogen

Recombinant Mouse Perforin-1 protein (21-554aa)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Description

  • This antibody has been tested in direct-ELISA Perforin is one of the major cytolytic proteins of cytolytic granules
  • Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
  • Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
  • Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
  • Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
  • Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
  • Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
  • Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
  • Alternative splicing results in multiple transcript variants of perforin.

Compare Similar Items

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Img

Thermo Scientific

PIPA5117488

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Antigen:
Perforin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRF1

Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18646

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA

Concentration:
2 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P10820

Gene Symbols:
PRF1

Immunogen:
Recombinant Mouse Perforin-1 protein (21-554aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117489

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Antigen:
PKA beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKACB

Gene Alias:
cAMP-dependent protein kinase C beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; Pkacb; PRKACB; protein kinase A catalytic subunit beta; protein kinase cAMP-activated catalytic subunit beta; protein kinase, cAMP dependent, catalytic, beta; protein kinase, cAMP-dependent, beta catalytic subunit; protein kinase, cAMP-dependent, catalytic, beta

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18749, 293508, 5567

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
6 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P22694, P68181, P68182

Gene Symbols:
PRKACB

Immunogen:
Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117490

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Antigen:
RASA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RASA1

Gene Alias:
CMAVM; CM-AVM; Gap; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; ras GTPase-activating protein 1-like protein; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; Rasa; RASA1; RASGAP; triphosphatase-activating protein; unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
218397, 5921

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
3.5 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P20936

Gene Symbols:
RASA1

Immunogen:
Recombinant Human Ras GTPase-activating protein 1 protein (201-500aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA5117491

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Antigen:
S100A9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
S100A9

Gene Alias:
60B8AG; AW546964; BEE22; BM-009; Cagb; calgranulin B; calgranulin-B; Calprotectin L1H subunit; CFAG; CGLB; DKFZp686B04128; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; LIAG; MAC387; Macrophage; MIF; Migration inhibitory factor-related protein 14; Monocyte; MRP14; MRP-14; MRP15; MRP16; myeloid-related protein 14; NIF; P14; protein S100-A9; S100 A9; S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a9

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20202

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
3 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P31725

Gene Symbols:
S100A9

Immunogen:
Recombinant Mouse Protein S100-A9 protein (2-113aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG