PIPA5117529
LATS2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117529-Each-of-1 | In Stock | ₹ 45,560.70 |
PIPA5117529 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,560.70
GST (18%): ₹ 8,200.926
Total Price: ₹ 53,761.626
Antigen
LATS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LATS2
Gene Alias
4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
567674
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
Western Blot
Concentration
3.06 mg/mL
Formulation
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
0
Gene Symbols
LATS2
Immunogen
Recombinant Zebrafish Large tumor suppressor kinase 2 protein (1022-1140aa)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Zebrafish
Product Type
Antibody
Isotype
IgG
Description
- This antibody has been tested in direct-ELISA LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family
- LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction
- LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity
- LATS2 plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity.
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Antigen: LATS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LATS2
Gene Alias: 4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 567674
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: Western Blot
Concentration: 3.06 mg/mL
Formulation: 10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: 0
Gene Symbols: LATS2
Immunogen: Recombinant Zebrafish Large tumor suppressor kinase 2 protein (1022-1140aa)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
LATS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LATS2
Gene Alias:
4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
567674
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
Western Blot
Concentration:
3.06 mg/mL
Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
0
Gene Symbols:
LATS2
Immunogen:
Recombinant Zebrafish Large tumor suppressor kinase 2 protein (1022-1140aa)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: notchl
Classification: Polyclonal
Conjugate: Unconjugated
Gene: notchl
Gene Alias: neurogenic locus notch homolog protein 1; Notch homolog; notch homolog, like; notch receptor, like; notchl
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 569522
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: Western Blot
Concentration: 2.509 mg/mL
Formulation: 10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: 0
Gene Symbols: notchl
Immunogen: Recombinant Zebrafish Notch homolog,-like protein (683-784aa)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
notchl
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
notchl
Gene Alias:
neurogenic locus notch homolog protein 1; Notch homolog; notch homolog, like; notch receptor, like; notchl
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
569522
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
Western Blot
Concentration:
2.509 mg/mL
Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
0
Gene Symbols:
notchl
Immunogen:
Recombinant Zebrafish Notch homolog,-like protein (683-784aa)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: Tyrosine Hydroxylase
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TH
Gene Alias: dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 30384
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: Western Blot
Concentration: 2.886 mg/mL
Formulation: 10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: 0
Gene Symbols: TH
Immunogen: Recombinant Zebrafish Tyrosine hydroxylase protein (1-110aa)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
Tyrosine Hydroxylase
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TH
Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
30384
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
Western Blot
Concentration:
2.886 mg/mL
Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
0
Gene Symbols:
TH
Immunogen:
Recombinant Zebrafish Tyrosine hydroxylase protein (1-110aa)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: SRC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRC
Gene Alias: ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 325084
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: Western Blot
Concentration: 2.464 mg/mL
Formulation: 10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q1JPZ3
Gene Symbols: SRC
Immunogen: Recombinant Zebrafish Proto-oncogene tyrosine-protein kinase Src protein (2-146aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
SRC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRC
Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
325084
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
Western Blot
Concentration:
2.464 mg/mL
Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q1JPZ3
Gene Symbols:
SRC
Immunogen:
Recombinant Zebrafish Proto-oncogene tyrosine-protein kinase Src protein (2-146aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG