PIPA5117713

TREX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117713-Each-of-1 In Stock ₹ 44,705.10

PIPA5117713 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TREX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TREX1

Gene Alias

1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11277

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9NSU2

Gene Symbols

TREX1

Immunogen

Recombinant Human Three-prime repair exonuclease 1 protein (1-270aa)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • This antibody has been tested in direct-ELISA Trex1 (ATRIP) is the major human 3' to 5' exonuclease which is required for checkpoint signaling after DNA damage
  • It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress
  • Trex1 is required for ATR expression
  • This gene uses two different open reading frames
  • The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint
  • The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human DNA polymerase III
  • Multiple transcript variants encoding different isoforms have been found
  • Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis.

Compare Similar Items

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Img

Thermo Scientific

PIPA5117713

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Antigen:
TREX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX1

Gene Alias:
1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11277

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9NSU2

Gene Symbols:
TREX1

Immunogen:
Recombinant Human Three-prime repair exonuclease 1 protein (1-270aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117714

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Antigen:
HIF1AN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIF1AN

Gene Alias:
2310046M24Rik; A830014H24Rik; DKFZp762F1811; factor inhibiting HIF1; factor inhibiting HIF-1; FIH; FIH 1; FIH1; FIH-1; FLJ20615; FLJ22027; Hif1an; hypoxia inducible factor 1 alpha subunit inhibitor; hypoxia inducible factor 1 subunit alpha inhibitor; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; Hypoxia-inducible factor asparagine hydroxylase; peptide-aspartate beta-dioxygenase

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
319594, 55662

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q8BLR9, Q9NWT6

Gene Symbols:
HIF1AN

Immunogen:
Recombinant Human Hypoxia-inducible factor 1-alpha inhibitor protein (2-254aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5117715

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Antigen:
Bacillus sp. UGL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
ugl; Unsaturated glucuronyl hydrolase

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Western Blot

Concentration:
3.5 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant Bacillus sp. Unsaturated glucuronyl hydrolase protein (1-377aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

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PIPA5117717

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Antigen:
n-Myc

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYCN

Gene Alias:
Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc); Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc); BHLHE37; Class E basic helix-loop-helix protein 37; c-nmyc; fb57a02; MODED; Mycn; mycn protein; MYCN proto-oncogene, bHLH transcription factor; neuroblastoma MYC oncogene; neuroblastoma myc-related oncogene 1; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; Nmuc1; NMYC; N-myc; N-myc protein; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; N-myc-like protein; ODED; oncogene NMYC; oncogene pp65/67; pp65/67; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); wu:fb57a02; zgc:85706

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
252851

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Western Blot

Concentration:
2.72 mg/mL

Formulation:
10mM PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q9PSJ0

Gene Symbols:
MYCN

Immunogen:
Recombinant Zebrafish N-myc protein (1-93aa)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG