PIPA5117770
AFAP1L2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117770-Each-of-1 | In Stock | ₹ 37,903.08 |
PIPA5117770 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,903.08
GST (18%): ₹ 6,822.554
Total Price: ₹ 44,725.634
Antigen
AFAP1L2
Classification
Polyclonal
Formulation
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.
Q8N4X5
Gene Symbols
AFAP1L2
Immunogen
E. coli-derived Human AFAP1L2 fragment
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Gene
AFAP1L2
Gene Alias
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
84632
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Related Products
Description
- AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites
- It interacts with and is phosphorylated by c-Src tyrosine kinase
- Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions
- Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer
- Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy
- At least four isoforms of AFAP1L2 are known to exist.
Compare Similar Items
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Antigen: AFAP1L2
Classification: Polyclonal
Formulation: PBS with 0.03% ProClin 300; pH 7
Gene Accession No.: Q8N4X5
Gene Symbols: AFAP1L2
Immunogen: E. coli-derived Human AFAP1L2 fragment
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: AFAP1L2
Gene Alias: actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 84632
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
AFAP1L2
Classification:
Polyclonal
Formulation:
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.:
Q8N4X5
Gene Symbols:
AFAP1L2
Immunogen:
E. coli-derived Human AFAP1L2 fragment
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
AFAP1L2
Gene Alias:
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
84632
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: AFP
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: P02771
Gene Symbols: AFP
Immunogen: Recombinant Human AFP/alpha-fetoprotein protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: AFP
Gene Alias: a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 174
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
AFP
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
P02771
Gene Symbols:
AFP
Immunogen:
Recombinant Human AFP/alpha-fetoprotein protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
AFP
Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
174
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: AGTPBP1
Classification: Polyclonal
Formulation: PBS with 0.03% ProClin 300; pH 7
Gene Accession No.: Q9UPW5
Gene Symbols: AGTPBP1
Immunogen: E. coli-derived Human AGTPBP1 fragment
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: AGTPBP1
Gene Alias: 1700020N17Rik; 2310001G17Rik; 2900054O13Rik; 4930445M19Rik; 5730402G09Rik; agtpbp1; ATP/GTP binding protein 1; ATP/GTP-binding protein 1; carboxypeptidase-tubulin; CCP1; Cytosolic carboxypeptidase 1; cytosolic carboxypeptidase 1; LOW QUALITY PROTEIN: cytosolic carboxypeptidase 1; Cytosolic carboxypeptidase 1-like protein; DKFZp686M20191; KIAA1035; Nervous system nuclear protein induced by axotomy protein 1; nervous system nuclear protein induced by axotomy protein 1 homolog; nmf243; Nna1; nuclear ATP/GTP-binding protein; pcd; Purkinje cell degeneration; si:ch73-236b16.2; soluble carboxypeptidase; tubulinyl-Tyr carboxypeptidase; tyrosine carboxypeptidase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23287
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
AGTPBP1
Classification:
Polyclonal
Formulation:
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.:
Q9UPW5
Gene Symbols:
AGTPBP1
Immunogen:
E. coli-derived Human AGTPBP1 fragment
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
AGTPBP1
Gene Alias:
1700020N17Rik; 2310001G17Rik; 2900054O13Rik; 4930445M19Rik; 5730402G09Rik; agtpbp1; ATP/GTP binding protein 1; ATP/GTP-binding protein 1; carboxypeptidase-tubulin; CCP1; Cytosolic carboxypeptidase 1; cytosolic carboxypeptidase 1; LOW QUALITY PROTEIN: cytosolic carboxypeptidase 1; Cytosolic carboxypeptidase 1-like protein; DKFZp686M20191; KIAA1035; Nervous system nuclear protein induced by axotomy protein 1; nervous system nuclear protein induced by axotomy protein 1 homolog; nmf243; Nna1; nuclear ATP/GTP-binding protein; pcd; Purkinje cell degeneration; si:ch73-236b16.2; soluble carboxypeptidase; tubulinyl-Tyr carboxypeptidase; tyrosine carboxypeptidase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23287
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: EMAP II
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: Q12904
Gene Symbols: Aimp1
Immunogen: Recombinant Human EMAP-II/AIMP1 Protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: Aimp1
Gene Alias: 9830137A06Rik; aaRS-interacting multifunctional protein 1; AIMP1; AIMP1/p43; AIMP1-PA; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; aminoacyl-tRNA synthetase-interacting multifunctional protein 1; ARS inducible multifunctional protein 1; ARS-interacting multifunctional protein 1; CG8235; CG8235-PA; Dmel\CG8235; Dmel_CG8235; EMAP2; EMAP-2; EMAPII; EMAP-II; endothelial monocyte activating polypeptide 2; endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; endothelial-monocyte activating polypeptide II; HLD3; mca1; multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; p43; SCYE1; Small inducible cytokine subfamily E member 1; small inducible cytokine subfamily E, member 1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9255
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
EMAP II
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
Q12904
Gene Symbols:
Aimp1
Immunogen:
Recombinant Human EMAP-II/AIMP1 Protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
Aimp1
Gene Alias:
9830137A06Rik; aaRS-interacting multifunctional protein 1; AIMP1; AIMP1/p43; AIMP1-PA; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; aminoacyl-tRNA synthetase-interacting multifunctional protein 1; ARS inducible multifunctional protein 1; ARS-interacting multifunctional protein 1; CG8235; CG8235-PA; Dmel\CG8235; Dmel_CG8235; EMAP2; EMAP-2; EMAPII; EMAP-II; endothelial monocyte activating polypeptide 2; endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; endothelial-monocyte activating polypeptide II; HLD3; mca1; multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; p43; SCYE1; Small inducible cytokine subfamily E member 1; small inducible cytokine subfamily E, member 1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9255
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG