PIPA5117837

CBF beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117837-Each-of-1 In Stock ₹ 37,903.08

PIPA5117837 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

CBF beta

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q13951

Gene Symbols

CBFB

Immunogen

E. coli-derived Human CBFB fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

CBFB

Gene Alias

AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

865

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2)
  • The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters
  • Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus
  • In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11
  • This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5117837

--


Antigen:
CBF beta

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q13951

Gene Symbols:
CBFB

Immunogen:
E. coli-derived Human CBFB fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CBFB

Gene Alias:
AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
865

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117839

--


Antigen:
CBWD1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9BRT8

Gene Symbols:
CBWD1

Immunogen:
E. coli-derived Human CBWD1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CBWD1

Gene Alias:
AV349248; BC018472; Cbwd1; Cobalamin synthase W domain-containing protein 1; cobalamin synthetase W domain-containing protein 1; COBP; COBW domain containing 1; COBW domain-containing protein 1; COBW domain-containing protein 1; COBW domain-containing protein 5; COBW-like protein; dopamine responsive protein; NPC-A-6; NPC-A-6 COBW domain-containing protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55871

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117840

--


Antigen:
CC2D1A

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q6P1N0

Gene Symbols:
CC2D1A

Immunogen:
E. coli-derived Human CC2D1A fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CC2D1A

Gene Alias:
5-HT1A receptor; AKI1; Akt kinase-interacting protein 1; BC016188; CC2D1A; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; five repressor element under dual repression-binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; Freud-1; Freud-1/Aki1; mental retardation, nonsyndromic, autosomal recessive, 3; MRT3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein; RGD1306108; Tape

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54862

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117841

--


Antigen:
CCAR1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q8IX12

Gene Symbols:
CCAR1

Immunogen:
E. coli-derived Human CCAR1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CCAR1

Gene Alias:
2610511G16Rik; 9430036H15Rik; Carp1; CARP-1; Ccar1; Cell cycle and apoptosis regulatory protein 1; cell division cycle and apoptosis regulator 1; cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; DIS; MGC44628; OTTHUMP00000019709; RGD1560358; RP11-437A18.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55749

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG