PIPA5117856

Cdc34 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117856-Each-of-1 In Stock ₹ 37,903.08

PIPA5117856 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

Cdc34

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

P49427

Gene Symbols

CDC34

Immunogen

E. coli-derived Human CDC34 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

CDC34

Gene Alias

(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

997

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
  • In vitro catalyzes 'Lys-48'-linked polyubiquitination
  • Cooperates with the E2 UBCH5C and the SCF (FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation
  • Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin
  • UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin
  • Cooperates with the SCF (SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1
  • Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles
  • Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation
  • Also involved in the degradation of beta-catenin
  • Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.

Compare Similar Items

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Img

Thermo Scientific

PIPA5117856

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Antigen:
Cdc34

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P49427

Gene Symbols:
CDC34

Immunogen:
E. coli-derived Human CDC34 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CDC34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AI327276; CDC34; cell division cycle 34; cell division cycle 34 homolog; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; serine protease; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme Cdc34; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
997

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117858

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Antigen:
MRCK beta

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9Y5S2

Gene Symbols:
CDC42BPB

Immunogen:
E. coli-derived Human CDC42BPB fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CDC42BPB

Gene Alias:
CDC42 binding protein kinase beta; CDC42 binding protein kinase beta (DMPK-like); CDC42-binding protein kinase beta; CDC42-binding protein kinase beta (DMPK-like); CDC42BPB; cdc42bpb {ECO:0000312; CDC42BP-beta; DMPK-like beta; EMBL:AAP34403.1}; Kiaa1124; MRCK beta; MRCKb; myotonic dystrophy kinase related CDC42 binding kinase beta; myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase like beta; myotonic dystrophy protein kinase-like beta; serine/threonine-protein kinase MRCK beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9578

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117859

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Antigen:
CDK1

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P06493

Gene Symbols:
CDK1

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human CDC2 Kinase/CDK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CDK1

Gene Alias:
5363; ABL1; cdc; CDC2; cdc-2; cdc2 kinase; CDC28A; Cdc2a; cdc2-a; cdc2Dm; cdc2x1.1; CDCDm; CDK1; Cdk-1; cdk1.S; CDK1/CDC2; CDK1-A; cdk1-b; Cdk1-PA; CDKN1; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; cell division control; cell division control protein 2 homolog; Cell division control protein 2 homolog 1; cell division control protein 2-A; cell division cycle 2 homolog A; cell division cycle 2 like; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; cell division protein kinase 1; Cell division protein kinase 1-A; CG5363; CG5363-PA; cyclin dependent kinase; cyclin dependent kinase 1; cyclin-dependent kinase; Cyclin-dependent kinase 1; cyclin-dependent kinase 1 S homeolog; cyclin-dependent kinase 1-A; D2366; Dcdc2; dCdk1; DKFZp686L20222; Dm cdc2; Dmcdc2; DmCdk1; Dmel\CG5363; Dmel_CG5363; DNA polymerase delta catalytic subunit; DNA polymerase III; DNA-directed DNA polymerase delta POL3; group 4; HPR6; KCIP-1; l(2)31Eh; LD38718p; maturation-promoting factor; MGC111195; MGC53829; MPF; OTTHUMP00000019660; P34 CDK1; P34 MGC111195; p34 protein kinase; p34 protein kinase 1; p34<CDC2>; p34cdc2; p34-cdc2 homologue; POL3; Protein 1054; protein 2; PSTAIR; TEX1; unnamed protein product; xcdc2; XELAEV_18036802mg; YDL102W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
983

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117863

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Antigen:
CES1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P23141

Gene Symbols:
CES1

Immunogen:
E. coli-derived Human CES1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
CES1

Gene Alias:
ACAT; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1A; carboxylesterase 1E; Carboxylesterase 1G; carboxylesterase 1-like; carboxylesterase 2 (liver); CE-1; CEH; Ces1; Ces-1; Ces1a; Ces1e; Ces1g; Ces1l; CES2; cholesteryl ester hydrolase; cocaine carboxylesterase; Eg; EG244595; Egasyn; Es22; Es-22; ES-HTEL; esterase 22; esterase-22; ES-x; Gm4976; hCE-1; HMSE; HMSE1; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; Liver carboxylesterase 22; liver carboxylesterase 3; methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; PCE-1; pI 5.5 esterase; REH; Retinyl ester hydrolase; serine esterase 1; SES1; Ses-1; TGH; triacylglycero; Triacylglycerol hydrolase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG