PIPA5117942

EXOSC7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117942-Each-of-1 In Stock ₹ 37,903.08

PIPA5117942 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

EXOSC7

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q15024

Gene Symbols

EXOSC7

Immunogen

E. coli-derived Human EXOSC7 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

EXOSC7

Gene Alias

2610002K22Rik; AV212732; EAP1; EGK_11725; EXOSC7; Exosome complex component RRP42; exosome complex exonuclease RRP42; exosome complex exonuclease RRP42; exosome complex component RRP42; Exosome complex exonuclease RRP42-like protein; exosome component 7; hRrp42p; hypothetical protein LOC550247; KIAA0116; mKIAA0116; p8; Ribosomal RNA-processing protein 42; RRP42; Rrp42p; zgc:110717

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23016

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
  • In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
  • The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
  • In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
  • It seems to be involved in degradation of histone mRNA
  • The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

Compare Similar Items

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Img

Thermo Scientific

PIPA5117942

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Antigen:
EXOSC7

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q15024

Gene Symbols:
EXOSC7

Immunogen:
E. coli-derived Human EXOSC7 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
EXOSC7

Gene Alias:
2610002K22Rik; AV212732; EAP1; EGK_11725; EXOSC7; Exosome complex component RRP42; exosome complex exonuclease RRP42; exosome complex exonuclease RRP42; exosome complex component RRP42; Exosome complex exonuclease RRP42-like protein; exosome component 7; hRrp42p; hypothetical protein LOC550247; KIAA0116; mKIAA0116; p8; Ribosomal RNA-processing protein 42; RRP42; Rrp42p; zgc:110717

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23016

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117945

--


Antigen:
FADS3

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300

Gene Accession No.:
Q9Y5Q0

Gene Symbols:
__

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human FADS3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
FADS3

Gene Alias:
AI464531; CYB5RP; cytochrome b5-related protein; delta(13) desaturase; Delta(13) fatty acid desaturase; delta-9 fatty acid desaturase; delta-9-desaturase; FADS3; Fatty acid desaturase 3; fatty acid desaturase 3; LOW QUALITY PROTEIN: fatty acid desaturase 3; linoleoyl-CoA desaturase (delta-9-desaturase)-like 3; LLCDL3; MNCb-0629; putative fatty acid desaturase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3995

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117946

--


Antigen:
FAM76B

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q5HYJ3

Gene Symbols:
Fam76b

Immunogen:
E. coli-derived Human FAM76B fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Fam76b

Gene Alias:
2810485I05Rik; C78303; FAM76B; family with sequence similarity 76 member B; family with sequence similarity 76, member B; protein FAM76B; RGD1311077

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
143684

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117947

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Antigen:
FBF1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q8TES7

Gene Symbols:
FBF1

Immunogen:
E. coli-derived Human FBF1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
FBF1

Gene Alias:
1110033G01Rik; 5930413D20; Alb; albatross; Fas (TNFRSF6) binding factor 1; Fas binding factor 1; Fas binding protein 1; fas-binding factor 1; Fbf1; FBF-1; KIAA1863; likely ortholog of H. sapiens Fas (TNFRSF6) binding factor 1 (FBF1); mKIAA1863; Protein albatross

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
85302

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG