PIPA5117962

GART Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117962-Each-of-1 In Stock ₹ 37,903.08

PIPA5117962 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

GART

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

P22102

Gene Symbols

GART

Immunogen

E. coli-derived Human GART fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

GART

Gene Alias

5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; Gaps; GAR transformylase; GARS; Gart; GARTF; glycinamide ribonucleotide formyltransferase; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosylamine--glycine ligase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; Trifunctional purine biosynthetic protein adenosine-3; Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2618

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • MERTK is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
  • Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
  • Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
  • MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
  • Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
  • Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

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Img

Thermo Scientific

PIPA5117962

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Antigen:
GART

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P22102

Gene Symbols:
GART

Immunogen:
E. coli-derived Human GART fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
GART

Gene Alias:
5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; Gaps; GAR transformylase; GARS; Gart; GARTF; glycinamide ribonucleotide formyltransferase; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosylamine--glycine ligase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; Trifunctional purine biosynthetic protein adenosine-3; Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2618

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117964

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Antigen:
GBP1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P32455

Gene Symbols:
GBP1

Immunogen:
E. coli-derived Human GBP1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
GBP1

Gene Alias:
GBP1; Gbp-1; Gbp2b; GTP-binding protein 1; guanine nucleotide-binding protein 1; guanylate binding protein 1; guanylate binding protein 1, interferon-inducible; guanylate binding protein 1, interferon-inducible, 67kDa; guanylate binding protein 2b; guanylate nucleotide binding protein 1; guanylate-binding protein 1; huGBP-1; interferon-gamma-inducible protein MAG-1; interferon-induced guanylate-binding protein 1; Mag-1; Mpa1; Mpa-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2633

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117965

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Antigen:
GDPGP1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q6ZNW5

Gene Symbols:
GDPGP1

Immunogen:
E. coli-derived Human GDPGP1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
GDPGP1

Gene Alias:
C15orf58; D330012F22Rik; GDP-D-glucose phosphorylase 1; GDP-D-glucose phosphorylase C15orf58; GDP-D-glucose phosphorylase C15orf58 homolog; GDPGP1; RGD1560277; VTC2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
390637

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5117966

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Antigen:
GFAP

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P14136

Gene Symbols:
GFAP

Immunogen:
E. coli-derived Human GFAP fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
GFAP

Gene Alias:
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2670

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG