PIPA5118030

Leptin Receptor Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118030-Each-of-1 In Stock ₹ 37,903.08

PIPA5118030 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

Leptin Receptor

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

P48356

Gene Symbols

Lepr

Immunogen

A synthetic peptide corresponding to the center region of the Mouse Leptin Receptor/LEPR

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

Lepr

Gene Alias

B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16847

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance
  • Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway
  • Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains
  • Several isoforms of the OB-R which differ in length and signaling capabilities have been reported
  • RNA transcripts encoding the OB-R long form have been found in the choroid plexus and in the hypothalamus which has been proposed as a control center for satiety and energy expenditure
  • Mutations in either the mouse OB-R (db) or leptin (ob) genes have been shown to result in early-onset obesity
  • Metabolic abnormalities attributable to these genotypes include hypercorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered CNS activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue.

Compare Similar Items

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Img

Thermo Scientific

PIPA5118030

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Antigen:
Leptin Receptor

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P48356

Gene Symbols:
Lepr

Immunogen:
A synthetic peptide corresponding to the center region of the Mouse Leptin Receptor/LEPR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
Lepr

Gene Alias:
B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16847

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118031

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Antigen:
Galectin 3

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P17931

Gene Symbols:
LGALS3

Immunogen:
E. coli-derived Human Galectin-3/LGALS3 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
LGALS3

Gene Alias:
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118034

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Antigen:
LPXN

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
O60711

Gene Symbols:
LPXN

Immunogen:
E. coli-derived Human LPXN fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
LPXN

Gene Alias:
4933402K05Rik; A530083L21Rik; AV278559; LDLP; LDPL; Leupaxin; LPXN

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9404

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118036

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Antigen:
LRRC59

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q96AG4

Gene Symbols:
Lrrc59

Immunogen:
E. coli-derived Human LRRC59 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Lrrc59

Gene Alias:
AA959742; C78668; hypothetical protein PRO1855; leucine rich repeat containing 59; leucine-rich repeat-containing protein 59; Leucine-rich repeat-containing protein 59, N-terminally processed; leucine-rich repeat-containing protein 59; LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 59; LRRC59; p34; PRO1855; Protein p34; Rbp34; Ribosome-binding protein p34

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55379

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG