PIPA5118069

MNAT1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5118069-Each-of-1 In Stock ₹ 37,903.08

PIPA5118069 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

MNAT1

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

P51948

Gene Symbols

Mnat1

Immunogen

E. coli-derived Human MNAT1 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

Mnat1

Gene Alias

AdoMet synthetase; AMS1; CAP35; CDK7/cyclin H assembly factor; CDK7/cyclin-H assembly factor; CDK-activating kinase assembly factor MAT1; cyclin G1 interacting protein; cyclin-G1-interacting protein; E130115E11Rik; EC 2.5.1.6; Mat1; MATA1; MAT-I/III; Menage a trois; menage a trois 1; menage a trois 1 (CAK assembly factor); menage a trois homolog 1, cyclin H assembly factor; menage a trois-like protein 1 cyclin H assembly factor; MNAT CDK-activating kinase assembly factor 1; MNAT1; MNAT1, CDK activating kinase assembly factor; p35; p36; RING finger protein 66; RING finger protein MAT1; RNF66; TFB3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4331

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • Progression through the cell cycle requires activation of a series of enzymes designated cyclin dependent kinases (Cdks)
  • The monomeric catalytic subunit, Cdk2, a critical enzyme for initiation of cell cycle progression, is completely inactive
  • Partial activation is achieved by the binding of regulatory cyclins such as cyclin D1, while full activation requires phosphorylation at Thr 160
  • The enzyme responsible for phosphorylation of Thr 160 in Cdk2 and also Thr 161 in Cdc2 p34, designated Cdk-activating kinase (CAK), has been partially purified and shown to be comprised of a catalytic subunit, a regulatory subunit and a subunit of unknown function
  • The regulatory subunit is a novel cyclin (cyclin H) and is required for activation of Cdk7
  • This previously undescribed protein, now termed Mat1, has been cloned as a protein that associates with the cyclin H-Cdk7 nuclear complex at all stages of the cell cycle
  • Cyclin H-Cdk7-Mat1 complexes display kinase activity towards Cdk activation domains, and the carboxy terminus of RNA polymerase II
  • Mat1 appears to constitute the first example of an assembly factor, essential for the formation of an active Cdk-cyclin complex.

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Img

Thermo Scientific

PIPA5118069

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Antigen:
MNAT1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P51948

Gene Symbols:
Mnat1

Immunogen:
E. coli-derived Human MNAT1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Mnat1

Gene Alias:
AdoMet synthetase; AMS1; CAP35; CDK7/cyclin H assembly factor; CDK7/cyclin-H assembly factor; CDK-activating kinase assembly factor MAT1; cyclin G1 interacting protein; cyclin-G1-interacting protein; E130115E11Rik; EC 2.5.1.6; Mat1; MATA1; MAT-I/III; Menage a trois; menage a trois 1; menage a trois 1 (CAK assembly factor); menage a trois homolog 1, cyclin H assembly factor; menage a trois-like protein 1 cyclin H assembly factor; MNAT CDK-activating kinase assembly factor 1; MNAT1; MNAT1, CDK activating kinase assembly factor; p35; p36; RING finger protein 66; RING finger protein MAT1; RNF66; TFB3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4331

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118070

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Antigen:
MRI1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9BV20

Gene Symbols:
MRI1

Immunogen:
E. coli-derived Human MRI1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
MRI1

Gene Alias:
2410018C20Rik; CH73-131E21.1; HAMAP-Rule:MF_03119}; M1Pi; M1Pi {ECO:0000255; mediator of RhoA-dependent invasion; Methylthioribose-1-phosphate isomerase; methylthioribose-1-phosphate isomerase {ECO:0000255; methylthioribose-1-phosphate isomerase 1; methylthioribose-1-phosphate isomerase homolog; methylthioribose-1-phosphate isomerase homolog (S. cerevisiae); MGC3207; MRDI; Mri1; MTNA; MTR-1-P isomerase; MTR-1-P isomerase {ECO:0000255; RGD1307789; similar to CG11334-PB, isoform B; S-methyl-5-thioribose-1-phosphate isomerase; S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255; S-methyl-5-thioribose-1-phosphate isomerase 1; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255; UNQ6390/PRO21135; Ypr118w; zgc:172216

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
84245

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118072

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Antigen:
MRPL15

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9P015

Gene Symbols:
Mrpl15

Immunogen:
E. coli-derived Human MRPL15 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Mrpl15

Gene Alias:
39S ribosomal protein L15, mitochondrial; HSPC145; L15mt; Mitochondrial large ribosomal subunit protein uL15m; mitochondrial ribosomal protein L15; Mrpl15; MRP-L15; MRP-L7; ribosomal protein, mitochondrial, L7; RPML7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29088

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118079

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Antigen:
MRPS10

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P82664

Gene Symbols:
MRPS10

Immunogen:
E. coli-derived Human MRPS10 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
MRPS10

Gene Alias:
1110038B19Rik; 28S ribosomal protein S10, mitochondrial; Ac1179; AW743084; Liver regeneration-related protein LRRG099; mitochondrial 28S ribosomal protein S10; mitochondrial ribosomal protein S10; Mitochondrial small ribosomal subunit protein uS10m; MRPS10; MRP-S10; MSTP040; PNAS-122; Rpms10; S10mt

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55173

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG