PIPA5118222

SHP-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118222-Each-of-1 In Stock ₹ 37,903.08

PIPA5118222 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

SHP-1

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

P29351

Gene Symbols

PTPN6

Immunogen

Recombinant Mouse PTPN6 Protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

ELISA, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

PTPN6

Gene Alias

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15170

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Description

  • SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
  • The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
  • SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
  • In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
  • Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
  • Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

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Thermo Scientific

PIPA5118222

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Antigen:
SHP-1

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P29351

Gene Symbols:
PTPN6

Immunogen:
Recombinant Mouse PTPN6 Protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15170

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118224

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Antigen:
PTPRCAP

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q14761

Gene Symbols:
PTPRCAP

Immunogen:
E. coli-derived Human PTPRCAP fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
PTPRCAP

Gene Alias:
AI605264; CD45 associated protein; CD-45-AP; CD45-AP; CD45-associated protein; LPAP; LSM-1; Lymphocyte phosphatase-associated phosphoprotein; protein tyrosine phosphatase receptor type C-associated protein; protein tyrosine phosphatase, receptor type C associated protein; protein tyrosine phosphatase, receptor type, C polypeptide-associated protein; protein tyrosine phosphatase, receptor type, C-associated protein; Ptprcap; PTPRC-associated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5790

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

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Thermo Scientific

PIPA5118225

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Antigen:
Bit1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q9Y3E5

Gene Symbols:
Ptrh2

Immunogen:
E. coli-derived Human PTRH2 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Ptrh2

Gene Alias:
A230072I16Rik; Bcl-2 inhibitor of transcription; bcl-2 inhibitor of transcription 1; BIT1; CFAP37; CGI-147; cilia and flagella associated protein 37; IMNEPD; OTTHUMP00000205936; peptidyl-tRNA hydrolase 2; peptidyl-tRNA hydrolase 2, mitochondrial; PTH; PTH 2; Pth2; Ptrh2; RGD1306819

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51651

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118232

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Antigen:
RABEP1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q15276

Gene Symbols:
RABEP1

Immunogen:
E. coli-derived Human RABEP1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
RABEP1

Gene Alias:
neurocrescin; rab GTPase-binding effector protein 1; RAB5 effector protein; RAB5EP; rabaptin 5; rabaptin, RAB GTPase binding effector protein 1; rabaptin-4; Rabaptin-5; rabaptin-5alpha; Rabep1; RABPT5; Rabpt5a; Renal carcinoma antigen NY-REN-17

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9135

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG