PIPA5118357

WASH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5118357-Each-of-1 In Stock ₹ 37,903.08

PIPA5118357 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

WASH1

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

A8K0Z3

Gene Symbols

WASHC1

Immunogen

E. coli-derived Human WASH1/WASHC1 fragment

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

WASHC1

Gene Alias

CXYorf1-like protein on chromosome 9; FAM39E; family with sequence similarity 39, member E; FLJ00075 protein; Protein FAM39E; WAS protein family homolog 1; WASH; WASH complex subunit 1; WASH1; WASHC1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100287171

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • WASHC1 (WASH1) is a protein coding gene with endocytosis as a related pathway
  • Acts as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting
  • Its assembly in the WASH core complex seems to inhibit its NPF activity and via WASHC2 is required for its membrane targeting
  • Involved in endocytic trafficking of EGF
  • Involved in transferrin receptor recycling
  • Regulates the trafficking of endosomal alpha5beta1 integrin to the plasma membrane and involved in invasive cell migration
  • In T-cells involved in endosome-to-membrane recycling of receptors including T-cell receptor (TCR), CD28 and ITGAL; proposed to be implicated in T cell proliferation and effector function
  • In dendritic cells involved in endosome-to-membrane recycling of major histocompatibility complex (MHC) class II probably involving retromer and subsequently allowing antigen sampling, loading and presentation during T-cell activation
  • Involved in Arp2/3 complex-dependent actin assembly driving Salmonella typhimurium invasion independent of ruffling
  • Involved in the exocytosis of MMP14 leading to matrix remodeling during invasive migration and implicating late endosome-to-plasma membrane tubular connections and cooperation with the exocyst complex
  • Involved in negative regulation of autophagy independently from its role in endosomal sorting by inhibiting BECN1 ubiquitination to inactivate PIK3C3/Vps34 activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5118357

--


Antigen:
WASH1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
A8K0Z3

Gene Symbols:
WASHC1

Immunogen:
E. coli-derived Human WASH1/WASHC1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
WASHC1

Gene Alias:
CXYorf1-like protein on chromosome 9; FAM39E; family with sequence similarity 39, member E; FLJ00075 protein; Protein FAM39E; WAS protein family homolog 1; WASH; WASH complex subunit 1; WASH1; WASHC1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100287171

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118364

--


Antigen:
YES1

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P07947

Gene Symbols:
Yes1

Immunogen:
E. coli-derived Human YES1 fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Yes1

Gene Alias:
cellular yes-1 protein; c-Src; c-Yes; EC 2.7.10.2; HsT441; p60c-yes; p60-Src; P61-YES; pp60c-src; Proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; tyrosine-protein kinase Yes; viral oncogene yes homolog; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamagichi sarcoma viral (v-yes-1) oncogene homolog 1; Yamaguchi sarcoma oncogene; Yamaguchi sarcoma viral (v-yes) oncogene homolog 1; Yamaguchi sarcoma viral oncogene homolog 1; Yes; YES proto-oncogene 1, Src family tyrosine kinase; Yes1; YES1 proto-oncogene, Src family tyrosine kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7525

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

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PIPA5118366

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Antigen:
14-3-3 eta

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
Q04917

Gene Symbols:
YWHAH

Immunogen:
A synthetic peptide corresponding to the center region of the Human 14-3-3 eta/YWHAH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
YWHAH

Gene Alias:
14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 14-3-3e; 1433F; fb93e02; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; wu:fb51h04; wu:fb93e02; YWHA1; YWHA114-3-3 eta; ywhag; YWHAH; zgc:63883; zgc:63883 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7533

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5118367

--


Antigen:
ZC3H7A

Classification:
Polyclonal

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q8IWR0

Gene Symbols:
ZC3H7A

Immunogen:
E. coli-derived Human ZC3H7A fragment

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
ZC3H7A

Gene Alias:
A430104C18Rik; AI447294; AW556219; FLJ20318; HSPC055; ZC3H7; ZC3H7A; ZC3HDC7; Zinc finger CCCH domain-containing protein 7A; Zinc finger CCCH domain-containing protein 7A-like protein; zinc finger CCCH type containing 7 A; zinc finger CCCH type domain containing 7; zinc finger CCCH-type containing 7A; zinc finger CCCH-type domain containing 7; zinc-finger protein AY163807

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG