PIPA5118977

Bcl-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5118977-Each-of-1 In Stock ₹ 38,416.44

PIPA5118977 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

Bcl-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12043

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P10417

Gene Symbols

Bcl2

Immunogen

Recombinant protein B-Cell Leukemia/Lymphoma 2. The antigen corresponds to amino acid range 2-208 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

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Img

Thermo Scientific

PIPA5118977

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Antigen:
Bcl-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12043

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P10417

Gene Symbols:
Bcl2

Immunogen:
Recombinant protein B-Cell Leukemia/Lymphoma 2. The antigen corresponds to amino acid range 2-208 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118979

--


Antigen:
UPB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UPB1

Gene Alias:
AI195023; Beta-alanine synthase; beta-ureidopropionase; beta-ureidopropionase 1; BUP1; BUP-1; N-carbamoyl-beta-alanine amidohydrolase; UPB1; ureidopropionase, beta; wu:fb69e03; zgc:64020

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51733

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9UBR1

Gene Symbols:
UPB1

Immunogen:
Recombinant protein Beta-ureidopropionase. The antigen corresponds to amino acid range 121-384 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118982

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Antigen:
Biliverdin Reductase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Blvra

Gene Alias:
0610006A11Rik; 2500001N03Rik; Biliverdin reductase A; biliverdin reductase A-like protein; biliverdin-IX alpha-reductase; BLVR; Blvra; BVR; BVR A; BVRA; EC 1.3.1.24; testis tissue sperm-binding protein Li 61n

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116599

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P46844

Gene Symbols:
Blvra

Immunogen:
Recombinant protein Biliverdin Reductase A. The antigen corresponds to amino acid range 10-279 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118983

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Antigen:
BLVRB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BLVRB

Gene Alias:
Biliverdin reductase B; biliverdin reductase B (flavin reductase (NADPH)); biliverdin-IX beta-reductase; BLVRB; BVRB; BVR-B; epididymis secretory protein Li 10; flavin reductase (NADPH); FLR; FR; GHBP; green heme-binding protein; HEL-S-10; NADPH; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U, member 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
645

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P30043

Gene Symbols:
BLVRB

Immunogen:
Recombinant protein Biliverdin Reductase B. The antigen corresponds to amino acid range 2-206 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG