PIPA5119008

CASP9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119008-Each-of-1 In Stock ₹ 38,416.44

PIPA5119008 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

CASP9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CASP9

Gene Alias

25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

842

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P55211

Gene Symbols

CASP9

Immunogen

Recombinant protein Caspase 9. The antigen corresponds to amino acid range 331-416 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
  • Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
  • Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
  • Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
  • Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
  • Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
  • Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
  • Caspase 9 is expressed in variety of human tissues
  • An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
  • Mutations in Caspase 9 affect brain development
  • In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
  • In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
  • Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5119008

--


Antigen:
CASP9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP9

Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
842

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P55211

Gene Symbols:
CASP9

Immunogen:
Recombinant protein Caspase 9. The antigen corresponds to amino acid range 331-416 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119009

--


Antigen:
CARD9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD9

Gene Alias:
CANDF2; card 9; Card9; caspase recruitment domain family member 9; caspase recruitment domain family, member 9; caspase recruitment domain protein 9; caspase recruitment domain-containing protein 9; Gm782; hCARD9; rCARD9; RP11-413M3.9

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64170

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9H257

Gene Symbols:
CARD9

Immunogen:
Recombinant protein Caspase Recruitment Domain Family, Member 9. The antigen corresponds to amino acid range 26-283 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119011

--


Antigen:
COMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Comt

Gene Alias:
Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1312

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P21964

Gene Symbols:
Comt

Immunogen:
Recombinant protein Catechol-O-Methyltransferase. The antigen corresponds to amino acid range 52-271 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119013

--


Antigen:
Cathepsin Z

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ctsz

Gene Alias:
AI787083; AU019819; carboxypeptidase LB; cathepsin B2; cathepsin IV; cathepsin P; Cathepsin X; cathepsin Y; cathepsin Z; cathepsin Z1; CTSX; CTSZ; cysteine-type carboxypeptidase; D2Wsu143e; lysosomal carboxypeptidase B; preprocathepsin P

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1522

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9UBR2

Gene Symbols:
Ctsz

Immunogen:
Recombinant protein Cathepsin Z. The antigen corresponds to amino acid range 24-303 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG