PIPA5119052

CBF beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119052-Each-of-1 In Stock ₹ 40,769.34

PIPA5119052 - Each of 1

₹ 40,769.34

In Stock

Quantity

1

Base Price: ₹ 40,769.34

GST (18%): ₹ 7,338.481

Total Price: ₹ 48,107.821

Antigen

CBF beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CBFB

Gene Alias

AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12400

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.9 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

Q08024

Gene Symbols

CBFB

Immunogen

Recombinant protein Core Binding Factor Beta Subunit. The antigen corresponds to amino acid range 1-187 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2)
  • The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters
  • Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus
  • In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11
  • This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5119052

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Antigen:
CBF beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBFB

Gene Alias:
AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12400

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.9 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q08024

Gene Symbols:
CBFB

Immunogen:
Recombinant protein Core Binding Factor Beta Subunit. The antigen corresponds to amino acid range 1-187 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119055

--


Antigen:
DCL-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd302

Gene Alias:
1110055L24Rik; AI159627; BIMLEC; CD302; CD302 antigen; CD302 molecule; CLEC13A; C-type lectin BIMLEC; C-type lectin domain family 13 member A; C-type lectin domain family 13, member A; DCL1; DCL-1; DEC205-associated C-type lectin 1; KIAA0022; RGD1307606; Type I transmembrane C-type lectin receptor DCL-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66205

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9DCG2

Gene Symbols:
Cd302

Immunogen:
Recombinant protein C-Type Lectin Domain Family 13, Member A. The antigen corresponds to amino acid range 21-225 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119056

--


Antigen:
CNP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPPC

Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic nucleotide 3' phosphodiesterase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNP1; CNP2; CNP-22; CNP-29; CNP-53; CNPase; C-type natriuretic peptide; C-type natriuretic peptide/factor; INT3; lbab; natriuretic peptide C; natriuretic peptide precursor C; natriuretic peptide precursor type C; natriuretic peptide type C; NOTCH3; NPPC; snake venom metalloprotease inhibitor 02D01-like; SVSP15

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4880

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P23582

Gene Symbols:
NPPC

Immunogen:
Recombinant protein C-Type Natriuretic Peptide. The antigen corresponds to amino acid range 33-125 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119057

--


Antigen:
Cyclin B1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P14635

Gene Symbols:
Ccnb1

Immunogen:
Recombinant protein Cyclin B. The antigen corresponds to amino acid range 239-433 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG