PIPA5119060
COX2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119060-Each-of-1 | In Stock | ₹ 38,416.44 |
PIPA5119060 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,416.44
GST (18%): ₹ 6,914.959
Total Price: ₹ 45,331.399
Antigen
COX2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5743
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P35354
Gene Symbols
PTGS2
Immunogen
Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
Compare Similar Items
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Antigen: COX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5743
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P35354
Gene Symbols: PTGS2
Immunogen: Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
COX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5743
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P35354
Gene Symbols:
PTGS2
Immunogen:
Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Cyclophilin 40
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPID
Gene Alias: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; 4930564J03Rik; cyclophilin 40; cyclophilin D; cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP40; CYP-40; CYPD; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; I79_011990; MGC33096; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; PPID; Ppidl; Ppif; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 361967
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q6DGG0
Gene Symbols: PPID
Immunogen: Recombinant protein Cyclophilin 40. The antigen corresponds to amino acid range 7-191 of the target protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cyclophilin 40
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPID
Gene Alias:
40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; 4930564J03Rik; cyclophilin 40; cyclophilin D; cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP40; CYP-40; CYPD; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; I79_011990; MGC33096; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; PPID; Ppidl; Ppif; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
361967
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q6DGG0
Gene Symbols:
PPID
Immunogen:
Recombinant protein Cyclophilin 40. The antigen corresponds to amino acid range 7-191 of the target protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdo1
Gene Alias: 1300002L19Rik; Cdo; CDO1; CDOI; CDO-I; cysteine dioxygenase 1, cytosolic; cysteine dioxygenase type 1; Cysteine dioxygenase type I; cysteine dioxygenase, type I; cytosolic cysteine dioxygenase 1; D18Ucla3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1036
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 0.99 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q16878
Gene Symbols: Cdo1
Immunogen: Recombinant protein Cysteine Dioxygenase I. The antigen corresponds to amino acid range 1-200 of the target protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CDO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cdo1
Gene Alias:
1300002L19Rik; Cdo; CDO1; CDOI; CDO-I; cysteine dioxygenase 1, cytosolic; cysteine dioxygenase type 1; Cysteine dioxygenase type I; cysteine dioxygenase, type I; cytosolic cysteine dioxygenase 1; D18Ucla3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1036
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
0.99 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q16878
Gene Symbols:
Cdo1
Immunogen:
Recombinant protein Cysteine Dioxygenase I. The antigen corresponds to amino acid range 1-200 of the target protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CRISP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CRISP1
Gene Alias: Acidic epididymal glycoprotein homolog; acidic epididymal glycoprotein-like 1; AEGL1; AEG-like protein; AEG-related protein; ARP; CRISP1; CRISP-1; cysteine rich secretory protein 1; cysteine-rich secretory protein 1; cysteine-rich secretory protein-1 delta; epididymis secretory protein Li 57; HEL-S-57; HSCRISP1D; HSCRISP1G; HUMARP
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11571
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q03401
Gene Symbols: CRISP1
Immunogen: Recombinant protein Cysteine Rich Secretory Protein 1. The antigen corresponds to amino acid range 20-244 of the target protein.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CRISP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CRISP1
Gene Alias:
Acidic epididymal glycoprotein homolog; acidic epididymal glycoprotein-like 1; AEGL1; AEG-like protein; AEG-related protein; ARP; CRISP1; CRISP-1; cysteine rich secretory protein 1; cysteine-rich secretory protein 1; cysteine-rich secretory protein-1 delta; epididymis secretory protein Li 57; HEL-S-57; HSCRISP1D; HSCRISP1G; HUMARP
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11571
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q03401
Gene Symbols:
CRISP1
Immunogen:
Recombinant protein Cysteine Rich Secretory Protein 1. The antigen corresponds to amino acid range 20-244 of the target protein.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG