PIPA5119078

TRAIL-R2 (DR5) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119078-Each-of-1 In Stock ₹ 38,416.44

PIPA5119078 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

TRAIL-R2 (DR5)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF10B

Gene Alias

apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8795

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.68 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

O14763

Gene Symbols

TNFRSF10B

Immunogen

Recombinant protein Death receptor 5. The antigen corresponds to amino acid range 234-435 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
  • DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
  • DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
  • Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
  • Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
  • Overexpression of DR5 induces apoptosis and activates NF-kappa-B
  • DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
  • Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5119078

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Antigen:
TRAIL-R2 (DR5)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10B

Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8795

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
O14763

Gene Symbols:
TNFRSF10B

Immunogen:
Recombinant protein Death receptor 5. The antigen corresponds to amino acid range 234-435 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119079

--


Antigen:
DOCK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DOCK4

Gene Alias:
5330406C03; 6330411N01Rik; AF263288; C030023J22; dedicator of cytokinesis 4; dedicator of cytokinesis protein 4; DOCK4; Kiaa0716; mKIAA0716; RGD1561724

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9732

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8N1I0

Gene Symbols:
DOCK4

Immunogen:
Recombinant protein Dedicator Of Cytokinesis 4. The antigen corresponds to amino acid range 1-300 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119080

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Antigen:
Defensin alpha-3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DEFA3

Gene Alias:
DEF3; DEFA3; defensin 3, neutrophil-specific; defensin alpha 3; Defensin, alpha 3; defensin, alpha 3, neutrophil-specific; HNP-2; HNP3; HNP-3; HP 3-56; HP-2; HP3; HP-3; Neutrophil defensin 2; Neutrophil defensin 3; neutrophil peptide 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1668

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P59666

Gene Symbols:
DEFA3

Immunogen:
Recombinant protein Defensin Alpha 3, Neutrophil Specific. The antigen corresponds to amino acid range 21-94 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119081

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Antigen:
CD148

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPRJ

Gene Alias:
AI450271; BET; Byp; CD148; CD148 antigen; colon tumor susceptibility 1; density enhanced phosphatase-1; density-enhanced phosphatase 1; DEP1; DEP-1; HPTP beta-like tyrosine phosphatase; HPTP eta; HPTPeta; human density enhanced phosphatase-1; protein tyrosine phosphatase, receptor type J; protein tyrosine phosphatase, receptor type, J; protein tyrosine phosphatase, receptor type, J polypeptide; protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; Ptprj; Receptor-type tyrosine-protein phosphatase eta; R-PTP-ETA; RPTPJ; R-PTP-J; Scc1; Scc-1; Susceptibility to colon cancer 1; susceptibility to colon cancer 1, mouse, homolog of

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5795

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q12913

Gene Symbols:
PTPRJ

Immunogen:
Recombinant protein Density Enhanced Phosphatase 1. The antigen corresponds to amino acid range 1061-1293 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG