PIPA5119252

LEPR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119252-Each-of-1 In Stock ₹ 38,416.44

PIPA5119252 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

LEPR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Lepr

Gene Alias

B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16847

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P48356

Gene Symbols

Lepr

Immunogen

Recombinant protein Leptin Receptor. The antigen corresponds to amino acid range 22-203 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance
  • Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway
  • Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains
  • Several isoforms of the OB-R which differ in length and signaling capabilities have been reported
  • RNA transcripts encoding the OB-R long form have been found in the choroid plexus and in the hypothalamus which has been proposed as a control center for satiety and energy expenditure
  • Mutations in either the mouse OB-R (db) or leptin (ob) genes have been shown to result in early-onset obesity
  • Metabolic abnormalities attributable to these genotypes include hypercorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered CNS activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue.

Compare Similar Items

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Img

Thermo Scientific

PIPA5119252

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Antigen:
LEPR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lepr

Gene Alias:
B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16847

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P48356

Gene Symbols:
Lepr

Immunogen:
Recombinant protein Leptin Receptor. The antigen corresponds to amino acid range 22-203 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119254

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Antigen:
GARP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRRC32

Gene Alias:
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
434215

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
G3XA59

Gene Symbols:
LRRC32

Immunogen:
Recombinant protein Leucine Rich Repeat Containing Protein 32. The antigen corresponds to amino acid range 400-643 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119255

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Antigen:
PIDD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIDD1

Gene Alias:
1200011D09Rik; AU042446; DKFZp434D229; leucine-rich and death domain containing; leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; Lrdd; MGC16925; p53 induced death domain protein 1; p53 protein induced, with death domain; p53-induced death domain protein 1; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; Pidd; Pidd1; PIDD-C; PIDD-CC; PIDD-N

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57913

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9ERV7

Gene Symbols:
PIDD1

Immunogen:
Recombinant protein Leucine Rich Repeats And Death Domain Containing Protein. The antigen corresponds to amino acid range 666-915 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119256

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Antigen:
SERPINB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Serpinb1a

Gene Alias:
1190005M04Rik; AI325983; Anti elastase; anti-elastase; EGK_14416; EI; EIA; ELANH2; epididymis luminal protein 57; epididymis secretory protein Li 27; HEL57; HEL-S-27; L M/N MN PI2; LEI; leukocyte elastase inhibitor; Leukocyte elastase inhibitor A; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; ovalbumin; peptidase inhibitor 2; PI2; PI-2; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) peptidase inhibitor, clade B, member 1a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a; serine (or cysteine) proteinase inhibitor, clade B, member 1a; serine protease inhibitor EIA; serpin; Serpin B1; Serpin B1a; serpin family B member 1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; Serpinb1; Serpinb1a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66222

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.59 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9D154

Gene Symbols:
Serpinb1a

Immunogen:
Recombinant protein Leukocyte Elastase Inhibitor. The antigen corresponds to amino acid range 184-368 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG