PIPA5119399

RNASEH2A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119399-Each-of-1 In Stock ₹ 40,769.34

PIPA5119399 - Each of 1

₹ 40,769.34

In Stock

Quantity

1

Base Price: ₹ 40,769.34

GST (18%): ₹ 7,338.481

Total Price: ₹ 48,107.821

Antigen

RNASEH2A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RNASEH2A

Gene Alias

2400006P09Rik; AGS4; Aicardi-Goutieres syndrome 4 protein; hypothetical protein LOC512830; hypothetical protein MGC56307; JUNB; ribonuclease H2 subunit A; ribonuclease H2, large subunit; ribonuclease H2, subunit A; ribonuclease HI; ribonuclease HI large subunit; Ribonuclease HI subunit A; ribonuclease HI, large subunit; RNase H(35); RNase H2 subunit A; RNase HI large subunit; Rnaseh2a; RNASEHI; RNHIA; RNHL; zgc:56307

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10535

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

O75792

Gene Symbols

RNASEH2A

Immunogen

Recombinant protein Ribonuclease H2 Subunit A. The antigen corresponds to amino acid range 1-299 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids
  • The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair
  • RNAse H2 is made up of three subunits; all three are required for RNAse activity
  • Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid
  • Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.

Compare Similar Items

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Img

Thermo Scientific

PIPA5119399

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Antigen:
RNASEH2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNASEH2A

Gene Alias:
2400006P09Rik; AGS4; Aicardi-Goutieres syndrome 4 protein; hypothetical protein LOC512830; hypothetical protein MGC56307; JUNB; ribonuclease H2 subunit A; ribonuclease H2, large subunit; ribonuclease H2, subunit A; ribonuclease HI; ribonuclease HI large subunit; Ribonuclease HI subunit A; ribonuclease HI, large subunit; RNase H(35); RNase H2 subunit A; RNase HI large subunit; Rnaseh2a; RNASEHI; RNHIA; RNHL; zgc:56307

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10535

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
O75792

Gene Symbols:
RNASEH2A

Immunogen:
Recombinant protein Ribonuclease H2 Subunit A. The antigen corresponds to amino acid range 1-299 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119403

--


Antigen:
REXO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
REXO2

Gene Alias:
1810038D15Rik; AW107347; C11orf61; CGI-114; Gm13138; novel KRAB box domain containing protein; oligoribonuclease, mitochondrial; OTTMUSG00000010655; reduced expression 2; REX2; REX2, RNA exonuclease 2 homolog; REX2, RNA exonuclease 2 homolog (S. cerevisiae); Rexo2; RFN; RNA exonuclease 2; RNA exonuclease 2 homolog; SFN; small fragment nuclease; SMFN

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25996

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9Y3B8

Gene Symbols:
REXO2

Immunogen:
Recombinant protein RNA Exonuclease 2 Homolog. The antigen corresponds to amino acid range 41-213 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119405

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Antigen:
SCRN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCRN1

Gene Alias:
2810019K23Rik; 6330535A03Rik; AI852905; Kiaa0193; mKIAA0193; Scrn1; secernin 1; secernin-1; SES1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9805

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q12765

Gene Symbols:
SCRN1

Immunogen:
Recombinant protein Secernin 1. The antigen corresponds to amino acid range 2-414 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5119406

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Antigen:
SEMA5B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEMA5B

Gene Alias:
AI893641; Kiaa1445; mKIAA1445; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B; sema G; Sema5b; Semag; semaphorin 5B; semaphorin-5B; Semaphorin-G; SemG; UNQ5867/PRO34001

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54437

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.81 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9P283

Gene Symbols:
SEMA5B

Immunogen:
Recombinant protein Semaphorin 5B. The antigen corresponds to amino acid range 36-161 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG