PIPA5119654
B7-H4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119654-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5119654 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
B7-H4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Vtcn1
Gene Alias
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
295322, 79679
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q501W4, Q7Z7D3
Gene Symbols
Vtcn1
Immunogen
Recombinant protein within human B7-H4 aa 25-259
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: SKBR3 cell and human colon tissue lysates, MCF-7, rat epididymid tissue, human breast tissue, human breast tissue, human kidney tissue
- Subcellular Location: Cell membrane
- B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
- Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
- B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
- B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
- Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
- B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
- Overexpression of B7-H4 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
- Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).
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Antigen: B7-H4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vtcn1
Gene Alias: B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 295322, 79679
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q501W4, Q7Z7D3
Gene Symbols: Vtcn1
Immunogen: Recombinant protein within human B7-H4 aa 25-259
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
B7-H4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vtcn1
Gene Alias:
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
295322, 79679
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q501W4, Q7Z7D3
Gene Symbols:
Vtcn1
Immunogen:
Recombinant protein within human B7-H4 aa 25-259
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TROP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TACSTD2
Gene Alias: 40kD glycoprotein, identified by monoclonal antibody GA733; C80403; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733; GA7331; GA733-1; gastrointestinal tumor-associated antigen GA7331; GP50; Ly97; lymphocyte antigen 97; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; parturition-related protein 1; Prp1; TACD2; TACSTD2; Trop2; truncated TACSTD2; tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4070
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P09758
Gene Symbols: TACSTD2
Immunogen: Recombinant protein within RFc-hTROP2 aa 27-274 (Extracellular)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TROP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TACSTD2
Gene Alias:
40kD glycoprotein, identified by monoclonal antibody GA733; C80403; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733; GA7331; GA733-1; gastrointestinal tumor-associated antigen GA7331; GP50; Ly97; lymphocyte antigen 97; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; parturition-related protein 1; Prp1; TACD2; TACSTD2; Trop2; truncated TACSTD2; tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4070
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P09758
Gene Symbols:
TACSTD2
Immunogen:
Recombinant protein within RFc-hTROP2 aa 27-274 (Extracellular)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HO-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMOX1
Gene Alias: bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15368, 3162
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P09601, P14901
Gene Symbols: HMOX1
Immunogen: Synthetic peptide of N-terminal human Heme Oxygenase 1 (HO-1)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HO-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMOX1
Gene Alias:
bK286B10; D8Wsu38e; heat shock protein 32; heat shock protein, 32-kD; heme orygenase 1; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1; heme oxygenase 1; heme oxygenase-1; Hemox; hemoxygenase; Heox; HEOXG; Hmox; Hmox1; HMOX1D; HO; Ho1; HO-1; Hsp32; P32 protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15368, 3162
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P09601, P14901
Gene Symbols:
HMOX1
Immunogen:
Synthetic peptide of N-terminal human Heme Oxygenase 1 (HO-1)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RUNX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RUNX2
Gene Alias: Acute myeloid leukemia 3 protein; AKV core binding factor; Aml3; AML-3; Cbf; Cbfa1; Cbfa-1; CBF-alpha-1; CCD; CCD1; CLCD; core binding factor alpha 1; core binding factor alpha 1 subunit; core-binding factor subunit alpha-1; core-binding factor, runt domain, alpha subunit 1; LOW QUALITY PROTEIN: runt-related transcription factor 2; LS3; Oncogene AML-3; Osf2; OSF-2; osteoblast-specific transcription factor 2; PEA2aA; PEA2-alpha A; PEBP2 alpha A; PEBP2A; Pebp2a1; PEBP2aA; PEBP2-alpha A; Pebpa2a; Polyomavirus enhancer-binding protein 2 alpha A subunit; runt domain, alpha subunit 1; runt related transcription factor 2; runt-related transcription factor 2; RUNX 2; RUNX family transcription factor 2; Runx2; RUNX-2; SL3/AKV core-binding factor alpha A subunit; SL3-3 enhancer factor 1 alpha A subunit; transcription factor RUNX2; transcription factor RUNX2/CBFA1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 860
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q13950
Gene Symbols: RUNX2
Immunogen: Synthetic peptide of C-terminal human RUNX2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RUNX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RUNX2
Gene Alias:
Acute myeloid leukemia 3 protein; AKV core binding factor; Aml3; AML-3; Cbf; Cbfa1; Cbfa-1; CBF-alpha-1; CCD; CCD1; CLCD; core binding factor alpha 1; core binding factor alpha 1 subunit; core-binding factor subunit alpha-1; core-binding factor, runt domain, alpha subunit 1; LOW QUALITY PROTEIN: runt-related transcription factor 2; LS3; Oncogene AML-3; Osf2; OSF-2; osteoblast-specific transcription factor 2; PEA2aA; PEA2-alpha A; PEBP2 alpha A; PEBP2A; Pebp2a1; PEBP2aA; PEBP2-alpha A; Pebpa2a; Polyomavirus enhancer-binding protein 2 alpha A subunit; runt domain, alpha subunit 1; runt related transcription factor 2; runt-related transcription factor 2; RUNX 2; RUNX family transcription factor 2; Runx2; RUNX-2; SL3/AKV core-binding factor alpha A subunit; SL3-3 enhancer factor 1 alpha A subunit; transcription factor RUNX2; transcription factor RUNX2/CBFA1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
860
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q13950
Gene Symbols:
RUNX2
Immunogen:
Synthetic peptide of C-terminal human RUNX2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG