PIPA5119762

MST1 (STK4) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119762-Each-of-1 In Stock ₹ 43,079.46

PIPA5119762 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

MST1 (STK4)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Stk4

Gene Alias

AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

311622, 58231, 6789

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q13043, Q9JI11

Gene Symbols

Stk4

Immunogen

Synthetic peptide within human MST1 aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: HepG2 cell lysate, THP-1 cell lysate, rat kidney tissue, human spleen tissue, human placenta tissue, mouse testis tissue
  • Subcellular Location: Cytoplasm, Nucleus
  • STK4 (MST1) is a serine/threonine kinase which may be involved in apoptosis
  • It is possible that this protein induces the chromatin condensation observed in this process
  • STK4 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5119762

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Antigen:
MST1 (STK4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Stk4

Gene Alias:
AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
311622, 58231, 6789

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q13043, Q9JI11

Gene Symbols:
Stk4

Immunogen:
Synthetic peptide within human MST1 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119763

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Antigen:
S100A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
S100A2

Gene Alias:
CAN19; EG628324; predicted gene, EG628324; Protein S100-A2; Protein S-100L; S100 calcium binding protein A2; S100 calcium-binding protein A2; S100a2; S100L

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100910139, 6273, 628324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P29034

Gene Symbols:
S100A2

Immunogen:
Recombinant protein within human S100A2 aa 1-98

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119765

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Antigen:
ADK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADK

Gene Alias:
2310026J05Rik; 5033405D03Rik; Adenosine 5'-phosphotransferase; adenosine kinase; ADK; AI255373; AI987814; AK; testicular tissue protein Li 14

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11534, 132, 25368

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P55263, P55264, Q64640

Gene Symbols:
ADK

Immunogen:
Recombinant protein within human ADK aa 1-200

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119766

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Antigen:
ASNA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GET3

Gene Alias:
1810048H22Rik; ARSA; arsA arsenite transporter, ATP-binding, homolog 1; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ARSA1; ARSA-I; Arsenical pump-driving ATPase; Arsenical resistance ATPase; arsenite-stimulated ATPase; arsenite-translocating ATPase; Arsenite-transporting ATPase; asna1; ASNA-I; ATPase asna1; ATPase GET3; GET3; guided entry of tail-anchored proteins factor 3, ATPase; hARSA-I; hASNA-I; MGC3821; si:dkey-121b10.2; Transmembrane domain recognition complex 40 kDa ATPase subunit; TRC40; wu:fd05d03; zgc:56540; zgc:56540 protein; zgc:86799

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
288919, 439

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O43681

Gene Symbols:
GET3

Immunogen:
Synthetic peptide within human ASNA1 aa 300-348

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG