PIPA5119927

WWTR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119927-Each-of-1 In Stock ₹ 43,079.46

PIPA5119927 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

WWTR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WWTR1

Gene Alias

2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

25937, 97064

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9EPK5, Q9GZV5

Gene Symbols

WWTR1

Immunogen

Recombinant protein within human TAZ aa 1-200/400

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: Human placenta tissue lysate, 293T cell lysate, human kidney tissue, mouse brain tissue, A549, HT-29
  • Subcellular Location: Cell membrane, Cytoplasm, Membrane, Nucleus
  • WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
  • In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
  • WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
  • WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5119927

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Antigen:
WWTR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25937, 97064

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9EPK5, Q9GZV5

Gene Symbols:
WWTR1

Immunogen:
Recombinant protein within human TAZ aa 1-200/400

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119928

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Antigen:
ATGL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PNPLA2

Gene Alias:
0610039C21Rik; 1110001C14Rik; adipose triglyceride lipase; ATGL; ATGL DESNUTRIN; calcium-independent phospholipase A2; Desnutrin; DKFZp667M109; FP17548; IPLA2 zeta; iPLA2zeta; IPLA2-zeta; mutant patatin-like phospholipase domain containing 2; patatin like phospholipase domain containing 2; patatin-like phospholipase domain containing 2; patatin-like phospholipase domain containing protein 2; patatin-like phospholipase domain-containing protein 2; PEDF R; PEDF-R; pigment epithelium-derived factor; plpl; plpl2; Pnpla2; RGD1309044; transport-secretion protein; Transport-secretion protein 2; transport-secretion protein 2.2; triglyceride hydrolase; TTS 2.2; TTS2; TTS2.2; TTS-2.2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57104

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q96AD5

Gene Symbols:
PNPLA2

Immunogen:
Synthetic peptide within human Adipose Triglyceride Lipase aa 450-504/504 (Lumenal)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119929

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Antigen:
PLCB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLCB1

Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; 3110043I21Rik; AI132408; EIEE12; inositoltrisphosphohydrolase; KIAA0581; mKIAA0581; monophosphatidylinositol phosphodiesterase; Phosphb; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-1; phosphoinositide-specific phospholipase c; phospholipase C; phospholipase C beta 1; phospholipase C, beta 1; phospholipase C, beta 1 (phosphoinositide-specific); Phospholipase C-beta1; phospholipase C-beta-1; phospholipase C-beta-1a; phospholipase C-I; PI-PLC; PLC'1; PLC154; PLC-154; Plcb; PLCB1; PLCB1A; PLCB1B; PLCbeta1; PLC-beta-1; PLC-I; RATPHOSPHB; triphosphoinositide phosphodiesterase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18795, 23236, 24654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P10687, Q9NQ66, Q9Z1B3

Gene Symbols:
PLCB1

Immunogen:
Recombinant protein within human Phospholipase C beta 1 aa 50-250/1216

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5119932

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Antigen:
SLC22A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slc22a2

Gene Alias:
2-Oct; hOCT2; OCT2; OCT2r; Orct2; Organic cation transporter 2; rOCT2; Slc22a2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2; solute carrier family 22, member 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20518, 29503, 6582

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O15244, O70577, Q9R0W2

Gene Symbols:
Slc22a2

Immunogen:
Recombinant protein within human SLC22A2 aa 44-150/555 (Extracellular)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG