PIPA5120021

Thioredoxin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120021-Each-of-1 In Stock ₹ 43,079.46

PIPA5120021 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

Thioredoxin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TXN

Gene Alias

ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116484, 22166, 7295

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.30 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P10599, P10639, P11232

Gene Symbols

TXN, Txn1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thioredoxin 1 (Trx1/Thioredoxin 1 (Trx1/TXN)) (NP_0033202)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: NCI-H460, MCF7, HT-29, SKOV3, Mouse kidney, Mouse liver, Rat liver
  • The target is usually found in the following locations: Cytoplasm, Nucleus, Secreted
  • Immunogen sequence: MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
  • Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
  • The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
  • Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
  • The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
  • Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
  • Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5120021

--


Antigen:
Thioredoxin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TXN

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116484, 22166, 7295

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.30 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10599, P10639, P11232

Gene Symbols:
TXN, Txn1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thioredoxin 1 (Trx1/Thioredoxin 1 (Trx1/TXN)) (NP_0033202)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120022

--


Antigen:
PCAF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KAT2B

Gene Alias:
A930006P13Rik; AI461839; AW536563; CAF; CREBBP-associated factor; histone acetylase PCAF; Histone acetyltransferase KAT2B; histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; Kat2b; Lysine acetyltransferase 2B; P/ PCAF; P/CAF; P300/CBP-associated factor; Pcaf; Spermidine acetyltransferase KAT2B

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18519, 301164, 8850

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.01 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q92831, Q9JHD1

Gene Symbols:
KAT2B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human KAT2B/PCAF (NP_0038753)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120025

--


Antigen:
GDF15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gdf15

Gene Alias:
Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9518

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.42 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q99988

Gene Symbols:
Gdf15

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_0048552)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5120026

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Antigen:
ATF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atf4

Gene Alias:
Activating transcription factor 4; activating transcription factor 4 (tax-responsive enhancer element B67); activating transcription factor 4a; activating transcription factor 4b1 (tax-responsive enhancer element B67); activating transcription factor ATF-4; ATF 4; atf4; Atf-4; atf4 {ECO:0000312; ATF4 protein; atf4a; atf4b1; C/ATF; C/EBP-related ATF; cAMP response element-binding protein 2; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB2; CREB-2; Cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; hypothetical protein LOC509107; OTTHUMP00000199130; rATF-4; RGD:621863}; tax-re; TaxREB67; TaxREB67 homolog; tax-responsive enhancer element B67; tax-responsive enhancer element-binding protein 67; Tax-responsive enhancer element-binding protein 67 homolog; TXREB; wu:fj01c08; wu:fk30b04; zgc:85951

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
468

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P18848

Gene Symbols:
Atf4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATF4 (NP_001666.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG