PIPA5120054

APAF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5120054-Each-of-1 In Stock ₹ 43,079.46

PIPA5120054 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

APAF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APAF1

Gene Alias

6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11783, 317, 78963

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.45 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

O14727, O88879, Q9EPV5

Gene Symbols

APAF1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 470-600 of human APAF1 (NP_863651.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: Jurkat, 293T, Mouse testis
  • The target is usually found in the following locations: Cytoplasm
  • Immunogen sequence: PHTLSPDQED CMYWYNFLAY HMASAKMHKE LCALMFSLDW IKAKTELVGP AHLIHEFVEY RHILDEKDCA VSENFQEFLS LNGHLLGRQP FPNIVQLGLC EPETSEVYQQ AKLQAKQEVD NGMLYLEWIN K APAF1 gene encodes a cytoplasmic protein that initiates apoptosis
  • This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
  • Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
  • The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
  • Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
  • Alternative splicing results in several transcript variants encoding different isoforms.

Compare Similar Items

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Thermo Scientific

PIPA5120054

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Antigen:
APAF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APAF1

Gene Alias:
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11783, 317, 78963

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
O14727, O88879, Q9EPV5

Gene Symbols:
APAF1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 470-600 of human APAF1 (NP_863651.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120056

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Antigen:
Ku70

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XRCC6

Gene Alias:
5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 5'-dRP/AP lyase Ku70; 70 kDa subunit of Ku antigen; 70kDa; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit; CT; CTA-216E10.7; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22p1; Ku autoantigen p70 subunit; ku autoantigen protein p70 homolog; Ku autoantigen, 70kDa; Ku p70; Ku70; Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa); Kup70; Lupus Ku autoantigen protein p70; ML8; OTTHUMP00000028581; thyroid autoantigen; thyroid autoantigen 70 kDa; thyroid autoantigen 70kD (Ku antigen); thyroid autoantigen 70kDa (Ku antigen); Thyroid-lupus autoantigen; thyroid-lupus autoantigen p70; TLAA; XELAEV_18023498mg; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair complementing defective repair in Chinese hamste

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14375, 25019, 2547

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P12956, P23475

Gene Symbols:
XRCC6

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 408-609 of human Ku70 (NP_0014601)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5120057

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Antigen:
IKK gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkg

Gene Alias:
1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKBKG; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16151, 309295, 8517

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O88522, Q6TMG5, Q9Y6K9

Gene Symbols:
Ikbkg

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-390 of human IKK gamma (NP_0036301)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120059

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Antigen:
FABP5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fabp5

Gene Alias:
C-FABP; Cutaneous fatty acid-binding protein; DA11; EFABP; E-FABP; E-FABPPAFABP; Epidermal-type fatty acid-binding protein; epithelial fatty acid-binding protein; Fabp5; Fabpe; fatty acid binding protein 5; fatty acid binding protein 5 (psoriasis-associated); fatty acid binding protein 5, epidermal; fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; uncharacterized protein LOC16592; keratinocyte lipid-binding protein; KFABP; Klbp; Mal1; PAFABP; PA-FABP; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2171

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q01469

Gene Symbols:
Fabp5

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FABP5 (NP_001435.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG