PIPA5120127

LSD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120127-Each-of-1 In Stock ₹ 43,079.46

PIPA5120127 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

LSD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KDM1A

Gene Alias

1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23028, 500569, 99982

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

0.89 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O60341, Q6ZQ88

Gene Symbols

KDM1A

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 365-515 of human KDM1 (NP_0558282)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: MCF7, 293T
  • The target is usually found in the following locations: Nucleus
  • Immunogen sequence: ANGQAVPKEK DEMVEQEFNR LLEATSYLSH QLDFNVLNNK PVSLGQALEV VIQLQEKHVK DEQIEHWKKI VKTQEELKEL LNKMVNLKEK IKELHQQYKE ASEVKPPRDI TAEFLVKSKH RDLTALCKEY DELAETQGKL EEKLQELEAN P LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
  • LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
  • This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
  • It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
  • LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
  • This protein may play a role in the repression of neuronal genes
  • Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
  • It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
  • Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.

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PIPA5120127

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Antigen:
LSD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM1A

Gene Alias:
1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23028, 500569, 99982

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.89 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O60341, Q6ZQ88

Gene Symbols:
KDM1A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 365-515 of human KDM1 (NP_0558282)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120128

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Antigen:
PAK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pak4

Gene Alias:
5730488L07Rik; AW555722; hypothetical protein LOC431769; im:5916170; Kiaa1142; mKIAA1142; p21 (CDKN1A)-activated kinase 4; p21 (RAC1) activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; p21(CDKN1A)-activated kinase 4; p21-activated kinase 4; Pak4; PAK-4; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; serine/threonine-protein kinase PAK 4; wu:fd12b01; zgc:92014

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
70584

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.65 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q8BTW9

Gene Symbols:
Pak4

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human PAK4 (NP_005875.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5120131

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Antigen:
PYCARD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYCARD

Gene Alias:
9130417A21Rik; Apoptosis-associated speck-like protein containing a CARD; Asc; CARD5; caspase recruitment domain-containing protein 5; hASC; mASC; MGC10332; Pycard; PYD and CARD domain containing; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; TMS; TMS1; TMS-1; TNS1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
282817, 29108, 66824

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.9 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
Q9EPB4, Q9ULZ3

Gene Symbols:
PYCARD

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-195 of human ASC/TMS1 (NP_0373902)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120134

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Antigen:
P-Glycoprotein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Abcb1a

Gene Alias:
ABC superfamily; P-glycoprotein; ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; ATP binding cassette subfamily B member 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette sub-family B member 1A; ATP-binding cassette sub-family B member 1B; ATP-binding cassette transporter subfamily B, member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, subfamily B (MDR/TAP), member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-binding cassette, subfamily B, member 1B; ATP-dependent translocase ABCB1; ATP-dependent translocase ABCB1; multidrug r

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18669, 18671

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P06795, P21447

Gene Symbols:
Abcb1a, Abcb1b

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 603-692 of human P Glycoprotein (NP_000918.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG