PIPA5120279
DLAT Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120279-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5120279 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
DLAT
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DLAT
Gene Alias
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1737, 235339, 81654
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.69 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P08461, P10515, Q8BMF4
Gene Symbols
DLAT
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 87-270 of human DLAT (NP_001922.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: HeLa, MCF7, HepG2, K-562, Mouse brain, Rat brain
- The target is usually found in the following locations: Mitochondrion matrix
- Immunogen sequence: SLPPHQKVPL PSLSPTMQAG TIARWEKKEG DKINEGDLIA EVETDKATVG FESLEECYMA KILVAEGTRD VPIGAIICIT VGKPEDIEAF KNYTLDSSAA PTPQAAPAPT PAATASPPTP SAQAPGSSYP PHMQVLLPAL SPTMTMGTVQ RWEKKVGEKL SEGDLLAEIE TDKATIGFEV QEEG DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC)
- PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A
- The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A
- Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies
- These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)
- In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed
- PBC eventually leads to cirrhosis and liver failure.
Compare Similar Items
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Antigen: DLAT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DLAT
Gene Alias: 6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1737, 235339, 81654
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.69 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P08461, P10515, Q8BMF4
Gene Symbols: DLAT
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 87-270 of human DLAT (NP_001922.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DLAT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DLAT
Gene Alias:
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1737, 235339, 81654
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.69 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P08461, P10515, Q8BMF4
Gene Symbols:
DLAT
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 87-270 of human DLAT (NP_001922.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDP1
Gene Alias: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; Gm1024; MGC119646; PDH; PDP; PDP 1; PDP1; PDPC; PDPC 1; PPM2A; Ppm2c; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 1; pyruvate dehyrogenase phosphatase catalytic subunit 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 381511, 54704, 54705
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 3.41 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: O88483, Q3UV70, Q9P0J1
Gene Symbols: PDP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDP1
Gene Alias:
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; Gm1024; MGC119646; PDH; PDP; PDP 1; PDP1; PDPC; PDPC 1; PPM2A; Ppm2c; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 1; pyruvate dehyrogenase phosphatase catalytic subunit 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
381511, 54704, 54705
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
3.41 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
O88483, Q3UV70, Q9P0J1
Gene Symbols:
PDP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD26
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DPP4
Gene Alias: ACT3; Activation molecule 3; ADABP; ADCP2; ADCP-2; ADCP-I; adenosine deaminase complexing protein; Adenosine deaminase complexing protein 2; bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 60 kDa soluble form; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV 60 kDa soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2); dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; Dpp-4; DPPIV; DPP-IV; GP110 glycoprotein; I79_016618; serine protease; T-cell activation antigen CD26; THAM; Thymocyte-activating molecule; TP103; WC10
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13482, 1803, 25253
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.86 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P14740, P27487, P28843
Gene Symbols: DPP4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-766 of human CD26/DPP4 (NP_001926.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD26
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DPP4
Gene Alias:
ACT3; Activation molecule 3; ADABP; ADCP2; ADCP-2; ADCP-I; adenosine deaminase complexing protein; Adenosine deaminase complexing protein 2; bile canaliculus domain-specific membrane glycoprotein; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 60 kDa soluble form; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV 60 kDa soluble form; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2); dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; Dpp-4; DPPIV; DPP-IV; GP110 glycoprotein; I79_016618; serine protease; T-cell activation antigen CD26; THAM; Thymocyte-activating molecule; TP103; WC10
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13482, 1803, 25253
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.86 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P14740, P27487, P28843
Gene Symbols:
DPP4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-766 of human CD26/DPP4 (NP_001926.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: XPD
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ERCC2
Gene Alias: AA407812; AU020867; AW240756; basic transcription factor 2 80 kDa subunit; BTF2 p80; COFS2; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; EM9; ERCC excision repair 2, TFIIH core complex helicase subunit; Ercc2; Ercc-2; excision repair cross-complementation group 2; excision repair cross-complementing rodent repair deficiency, complementation group 2; General transcription and DNA repair factor IIH helicase subunit XPD; MGC102762; MGC126218; MGC126219; TFIIH; TFIIH 80 kDa subunit; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH p80; TFIIH subunit XPD; TTD; TTD1; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein; XPD; XPDC
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13871, 2068, 308415
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.69 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: O08811, P18074
Gene Symbols: ERCC2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human XPD/XPD/ERCC2 (NP_0011243391)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
XPD
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ERCC2
Gene Alias:
AA407812; AU020867; AW240756; basic transcription factor 2 80 kDa subunit; BTF2 p80; COFS2; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; EM9; ERCC excision repair 2, TFIIH core complex helicase subunit; Ercc2; Ercc-2; excision repair cross-complementation group 2; excision repair cross-complementing rodent repair deficiency, complementation group 2; General transcription and DNA repair factor IIH helicase subunit XPD; MGC102762; MGC126218; MGC126219; TFIIH; TFIIH 80 kDa subunit; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH p80; TFIIH subunit XPD; TTD; TTD1; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein; XPD; XPDC
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13871, 2068, 308415
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.69 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
O08811, P18074
Gene Symbols:
ERCC2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human XPD/XPD/ERCC2 (NP_0011243391)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG