PIPA5120325
Cortactin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120325-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5120325 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
Cortactin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cttn
Gene Alias
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13043, 2017, 60465
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.91 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q14247, Q60598, Q66HL2
Gene Symbols
Cttn
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Cortactin (NP_612632.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: MCF7, HeLa
- The target is usually found in the following locations: Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Membrane, Peripheral membrane protein, cell cortex, clathrin-coated pit, cytoskeleton, dendrite, dendritic spine, focal adhesion, lamellipodium, podosome, ruffle
- Immunogen sequence: MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG KTEKHESQRD YSKGFGGKYG Cortactin (Cttn) is a ubiquitous actin-binding protein that was originally identified as a substrate for Src
- It contributes to the organization of the actin cytoskeleton and cell shape
- Cortactin also plays a role in the formation of lamellipodia and cell migration
- It is accumulated in peripheral, actin-enriched structures of cells suggesting that cortactin facilitates actin network formation
- Cortactin has four major domains of interest the N-terminal acidic (NTA) and tandem repeats domains and the C-terminal proline-rich and SH3 Domains
- NTA associates with the Arp2/3 and WASP complex at F-actin branches
- Cortactin is involved in promoting cell motility and invasion, including a critical role in invadopodia, actin rich-subcellular protrusions associated with degradation of the ECM by cancer cells
- Cortactin is phosphorylated by src family kinases at Y421, Y466, and Y482 and S405 and S418 that are phosphorylated by Erk family kinases.
Compare Similar Items
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Antigen: Cortactin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cttn
Gene Alias: 1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13043, 2017, 60465
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.91 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q14247, Q60598, Q66HL2
Gene Symbols: Cttn
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Cortactin (NP_612632.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cortactin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cttn
Gene Alias:
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13043, 2017, 60465
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.91 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q14247, Q60598, Q66HL2
Gene Symbols:
Cttn
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Cortactin (NP_612632.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TET1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TET1
Gene Alias: 2510010B09Rik; AA517754; bA119F7.1; BB001228; CXXC finger 6; CXXC zinc finger 6; CXXC6; CXXC-type zinc finger protein 6; D10Ertd17e; KIAA1676; LCX; leukemia-associated protein with a CXXC domain; Methylcytosine dioxygenase TET1; mKIAA1676; MLL-TET1; RP11-119F7.1; Ten-eleven translocation 1 gene protein; ten-eleven translocation 1 gene protein homolog; ten-eleven translocation-1; tet methylcytosine dioxygenase 1; tet oncogene 1; Tet1; TET1 splice variant VP_DE4; TET1 splice variant VP_DE456; TET1-MLL
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 309902, 52463, 80312
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.7 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: Q3URK3, Q8NFU7
Gene Symbols: TET1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1800-1900 of human TET1 (NP_0851282)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TET1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TET1
Gene Alias:
2510010B09Rik; AA517754; bA119F7.1; BB001228; CXXC finger 6; CXXC zinc finger 6; CXXC6; CXXC-type zinc finger protein 6; D10Ertd17e; KIAA1676; LCX; leukemia-associated protein with a CXXC domain; Methylcytosine dioxygenase TET1; mKIAA1676; MLL-TET1; RP11-119F7.1; Ten-eleven translocation 1 gene protein; ten-eleven translocation 1 gene protein homolog; ten-eleven translocation-1; tet methylcytosine dioxygenase 1; tet oncogene 1; Tet1; TET1 splice variant VP_DE4; TET1 splice variant VP_DE456; TET1-MLL
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
309902, 52463, 80312
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.7 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
Q3URK3, Q8NFU7
Gene Symbols:
TET1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1800-1900 of human TET1 (NP_0851282)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RABIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RABIF
Gene Alias: AI842864; AW549708; E130318E12Rik; Guanine nucleotide exchange factor MSS4; guanine-nucleotide-releasing protein mss4; mammalian suppressor of SEC4; Mss4; RAB interacting factor; RABIF; RAB-interacting factor; RASGFR3; RASGRF3; Ras-specific guanine-releasing factor 3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 304807, 5877, 98710
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.36 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P47224, Q08326, Q91X96
Gene Symbols: RABIF
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human RABIF (NP_002862.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RABIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RABIF
Gene Alias:
AI842864; AW549708; E130318E12Rik; Guanine nucleotide exchange factor MSS4; guanine-nucleotide-releasing protein mss4; mammalian suppressor of SEC4; Mss4; RAB interacting factor; RABIF; RAB-interacting factor; RASGFR3; RASGRF3; Ras-specific guanine-releasing factor 3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
304807, 5877, 98710
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P47224, Q08326, Q91X96
Gene Symbols:
RABIF
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human RABIF (NP_002862.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SSTR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SSTR2
Gene Alias: Smstr2; Smstr-2; somatostatin receptor; somatostatin receptor 2; somatostatin receptor 2a; somatostatin receptor subtype 2; somatostatin receptor type 2; somatotropin release-inhibiting factor receptor; SRIF-1; SS2R; SS-2-R; SS2-R; SSR2; sst2; Sstr2; SSTR-2; SSTR2A
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20606, 54305, 6752
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.45 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P30680, P30874, P30875
Gene Symbols: SSTR2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 270-369 of human Somatostatin Receptor 2 (SSTR2) (NP_0010411)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SSTR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SSTR2
Gene Alias:
Smstr2; Smstr-2; somatostatin receptor; somatostatin receptor 2; somatostatin receptor 2a; somatostatin receptor subtype 2; somatostatin receptor type 2; somatotropin release-inhibiting factor receptor; SRIF-1; SS2R; SS-2-R; SS2-R; SSR2; sst2; Sstr2; SSTR-2; SSTR2A
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20606, 54305, 6752
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.45 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P30680, P30874, P30875
Gene Symbols:
SSTR2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 270-369 of human Somatostatin Receptor 2 (SSTR2) (NP_0010411)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG