PIPA5120433
LATS2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120433-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5120433 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
LATS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LATS2
Gene Alias
4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26524, 305922, 50523
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.21 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q7TSJ6, Q9NRM7
Gene Symbols
LATS2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 70-145 of human LATS2 (NP_0553872)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Positive test controls include: Mouse testis, Rat lung, Rat testis, Rat kidney
- The target is usually found in the following locations: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, spindle pole
- Immunogen sequence: FGPYQKALRE IRYSLLPFAN ESGTSAAAEV NRQMLQELVN AGCDQEMAGR ALKQTGSRSI EAALEYISKM GYLDPR LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family
- LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction
- LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity
- LATS2 plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity.
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Antigen: LATS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LATS2
Gene Alias: 4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26524, 305922, 50523
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.21 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q7TSJ6, Q9NRM7
Gene Symbols: LATS2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 70-145 of human LATS2 (NP_0553872)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LATS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LATS2
Gene Alias:
4932411G09Rik; AV277261; AW228608; h-warts; Kinase phosphorylated during mitosis protein; KPM; large tumor suppressor 2; large tumor suppressor homolog 2; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; LATS2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; si:ch211-173o4.2; Warts-like kinase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26524, 305922, 50523
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.21 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q7TSJ6, Q9NRM7
Gene Symbols:
LATS2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-145 of human LATS2 (NP_0553872)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACSL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACSL1
Gene Alias: Acas; Acas1; ACS; Acs1; ACSL1; Acsl2; Acyl CoA synthetase, long chain; acyl-CoA synthetase 1; acyl-CoA synthetase long chain family member 1; acyl-CoA synthetase long-chain family member 1; Arachidonate--CoA ligase; COAA; FACL1; Facl2; FACS; fatty acid Coenzyme A ligase, long chain 2; fatty-acid-Coenzyme A ligase long chain 2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; L LACS2; LACS; LACS 1; LACS 2; LACS1; LACS2; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; long-chain-fatty-acid--CoA ligase 1; Long-chain-fatty-acid--CoA ligase, liver isozyme; OTTHUMP00000218457; OTTHUMP00000218460; OTTHUMP00000218462; OTTHUMP00000218465; palmitoyl-CoA ligase; Palmitoyl-CoA ligase 1; palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; Phytanate--CoA ligase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14081, 2180, 25288
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.64 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P18163, P33121, P41216
Gene Symbols: ACSL1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 46-145 of human ACSL1 (NP_001986.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACSL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACSL1
Gene Alias:
Acas; Acas1; ACS; Acs1; ACSL1; Acsl2; Acyl CoA synthetase, long chain; acyl-CoA synthetase 1; acyl-CoA synthetase long chain family member 1; acyl-CoA synthetase long-chain family member 1; Arachidonate--CoA ligase; COAA; FACL1; Facl2; FACS; fatty acid Coenzyme A ligase, long chain 2; fatty-acid-Coenzyme A ligase long chain 2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; L LACS2; LACS; LACS 1; LACS 2; LACS1; LACS2; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; long-chain-fatty-acid--CoA ligase 1; Long-chain-fatty-acid--CoA ligase, liver isozyme; OTTHUMP00000218457; OTTHUMP00000218460; OTTHUMP00000218462; OTTHUMP00000218465; palmitoyl-CoA ligase; Palmitoyl-CoA ligase 1; palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; Phytanate--CoA ligase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14081, 2180, 25288
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.64 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P18163, P33121, P41216
Gene Symbols:
ACSL1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 46-145 of human ACSL1 (NP_001986.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ALDH3A2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ALDH3A2
Gene Alias: Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; fatty aldehyde dehydrogenase; Fatty aldehyde dehydrogenase-like protein; FLJ20851; microsomal aldehyde dehydrogenase; msALDH; QccE-15682; SLS
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11671, 224, 65183
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.13 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P30839, P47740, P51648
Gene Symbols: ALDH3A2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human ALDH3A2 (NP_001026976.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ALDH3A2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ALDH3A2
Gene Alias:
Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; fatty aldehyde dehydrogenase; Fatty aldehyde dehydrogenase-like protein; FLJ20851; microsomal aldehyde dehydrogenase; msALDH; QccE-15682; SLS
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11671, 224, 65183
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P30839, P47740, P51648
Gene Symbols:
ALDH3A2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human ALDH3A2 (NP_001026976.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GSTA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GSTA1
Gene Alias: 13-hydroperoxyoctadecadienoate peroxidase; Androst-5-ene-3,17-dione isomerase; class alpha; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase; glutathione S-transferase 2; glutathione S-transferase A1; Glutathione S-transferase A1, N-terminally processed; glutathione S-transferase A3 subunit; glutathione S-transferase A5; glutathione S-transferase alpha 1; glutathione S-transferase alpha M14; Glutathione S-transferase alpha M14, N-terminally processed; Glutathione S-transferase alpha-3; glutathione S-transferase Ha subunit 1; glutathione S-transferase Ya; Glutathione S-transferase Ya1; glutathione S-transferase Yc-1; glutathione S-transferase Yc1 subunit; glutathione S-transferase, alpha 1 (Ya); Glutathione-S-transferase alpha type (Ya); GST; GST 2-2; GST A3-3; GST AA; GST class-alpha; GST class-alpha member 1; GST HA subunit 1; GST Yc1; GST2; Gst2-1; Gsta; GSTA1; GSTA1-1; Gsta3; Gsta5; GST-epsilon; Gstya; Gstyc1; GTH1; OTTMUSG00000031890; R
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14857
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.54 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P13745
Gene Symbols: GSTA1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA1 (NP_665683.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
GSTA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GSTA1
Gene Alias:
13-hydroperoxyoctadecadienoate peroxidase; Androst-5-ene-3,17-dione isomerase; class alpha; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase; glutathione S-transferase 2; glutathione S-transferase A1; Glutathione S-transferase A1, N-terminally processed; glutathione S-transferase A3 subunit; glutathione S-transferase A5; glutathione S-transferase alpha 1; glutathione S-transferase alpha M14; Glutathione S-transferase alpha M14, N-terminally processed; Glutathione S-transferase alpha-3; glutathione S-transferase Ha subunit 1; glutathione S-transferase Ya; Glutathione S-transferase Ya1; glutathione S-transferase Yc-1; glutathione S-transferase Yc1 subunit; glutathione S-transferase, alpha 1 (Ya); Glutathione-S-transferase alpha type (Ya); GST; GST 2-2; GST A3-3; GST AA; GST class-alpha; GST class-alpha member 1; GST HA subunit 1; GST Yc1; GST2; Gst2-1; Gsta; GSTA1; GSTA1-1; Gsta3; Gsta5; GST-epsilon; Gstya; Gstyc1; GTH1; OTTMUSG00000031890; R
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14857
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.54 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P13745
Gene Symbols:
GSTA1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA1 (NP_665683.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG