PIPA5120437
MCU Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120437-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5120437 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
MCU
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCU
Gene Alias
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
215999, 294560, 90550
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
3.86 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
Q3UMR5, Q8NE86
Gene Symbols
MCU
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 51-170 of human MCU (NP_6123661)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Positive test controls include: HepG2
- Immunogen sequence: VHQRIASWQN LGAVYCSTVV PSDDVTVVYQ NGLPVISVRL PSRRERCQFT LKPISDSVGV FLRQLQEEDR GIDRVAIYSP DGVRVAASTG IDLLLLDDFK LVINDLTYHV RPPKRDLLSH Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria
- Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex)
- Activity is regulated by MICU1 and MICU2
- At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity
- Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
- Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes
- While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a 'fight-or-flight' response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells
- participates in mitochondrial permeability transition during ischemia-reperfusion injury
- Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake
- Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults
- Regulates synaptic vesicle endocytosis kinetics in central nerve terminal
- Involved in antigen processing and presentation.
Compare Similar Items
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Antigen: MCU
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCU
Gene Alias: 2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 215999, 294560, 90550
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 3.86 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: Q3UMR5, Q8NE86
Gene Symbols: MCU
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 51-170 of human MCU (NP_6123661)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MCU
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCU
Gene Alias:
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
215999, 294560, 90550
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
3.86 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
Q3UMR5, Q8NE86
Gene Symbols:
MCU
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 51-170 of human MCU (NP_6123661)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Opsin 4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: OPN4
Gene Alias: 1110007J02Rik; Gm533; LOC721663; Melanopsin; MGC142118; MOP; Mopn; OPN 4; OPN4; opn4 {ECO:0000312; opsin 4; opsin 4 (melanopsin); opsin-4; RGD:621701}
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192223, 94233
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.34 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q8R456, Q9UHM6
Gene Symbols: OPN4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Opsin 4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
OPN4
Gene Alias:
1110007J02Rik; Gm533; LOC721663; Melanopsin; MGC142118; MOP; Mopn; OPN 4; OPN4; opn4 {ECO:0000312; opsin 4; opsin 4 (melanopsin); opsin-4; RGD:621701}
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192223, 94233
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.34 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q8R456, Q9UHM6
Gene Symbols:
OPN4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ARL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Arl3
Gene Alias: ADP ribosylation factor like GTPase 3; ADP-ribosylation factor like GTPase 3; ADP-ribosylation factor-like 3; ADP-ribosylation factor-like protein 3; ADP-ribosylation-like 3; ARD3; ARFL3; ARF-like 3; Arf-like protein 3; Arl3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 403, 56350, 64664
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.2 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P36405, P37996, Q9WUL7
Gene Symbols: Arl3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human ARL3 (NP_004302.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ARL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Arl3
Gene Alias:
ADP ribosylation factor like GTPase 3; ADP-ribosylation factor like GTPase 3; ADP-ribosylation factor-like 3; ADP-ribosylation factor-like protein 3; ADP-ribosylation-like 3; ARD3; ARFL3; ARF-like 3; Arf-like protein 3; Arl3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
403, 56350, 64664
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P36405, P37996, Q9WUL7
Gene Symbols:
Arl3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human ARL3 (NP_004302.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BCAT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bcat1
Gene Alias: BCAT(c); Bcat1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino acid transaminase 1, cytosolic; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; cytosolic branched-chain amino acid aminotransferase; Eca39; MECA39; placental protein 18; PNAS121; PP18; Protein ECA39
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12035, 29592, 586
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.29 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P24288, P54687, P54690
Gene Symbols: Bcat1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BCAT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bcat1
Gene Alias:
BCAT(c); Bcat1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino acid transaminase 1, cytosolic; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; branched-chain-amino-acid aminotransferase, cytosolic; cytosolic branched-chain amino acid aminotransferase; Eca39; MECA39; placental protein 18; PNAS121; PP18; Protein ECA39
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12035, 29592, 586
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.29 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P24288, P54687, P54690
Gene Symbols:
Bcat1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG