PIPA5120483

PEDF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120483-Each-of-1 In Stock ₹ 43,079.46

PIPA5120483 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

PEDF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SERPINF1

Gene Alias

AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20317, 5176

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.89 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P36955, P97298

Gene Symbols

SERPINF1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 141-240 of human PEDF/SERPINF1 (NP_0026063)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: HepG2, Mouse liver, Human serum
  • The target is usually found in the following locations: Melanosome, Secreted
  • Immunogen sequence: RIVFEKKLRI KSSFVAPLEK SYGTRPRVLT GNPRLDLQEI NNWVQAQMKG KLARSTKEIP DEISILLLGV AHFKGQWVTK FDSRKTSLED FYLDEERTVR PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties
  • It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body
  • A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells
  • In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2
  • The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins
  • The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin
  • To date, PEDF-R is the only signaling receptor known to be used by a serpin family member
  • The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR)
  • PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers.

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Thermo Scientific

PIPA5120483

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Antigen:
PEDF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINF1

Gene Alias:
AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20317, 5176

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.89 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P36955, P97298

Gene Symbols:
SERPINF1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 141-240 of human PEDF/SERPINF1 (NP_0026063)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120485

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Antigen:
VPARP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PARP4

Gene Alias:
193 kDa vault protein; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; ADP-ribosyltransferase diphtheria toxin-like 4; ADPRTL1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; H5 proline-rich; I-alpha-I-related; KIAA0177; p193; Parp4; PARP-4; PARPL; PARP-related; PARP-related/IalphaI-related H5/proline-rich; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; poly [ADP-ribose] polymerase 4; poly(ADP-ribose) polymerase family member 4; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase-like 1; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; vault protein, 193-kDa; VAULT3; von Willebrand factor A domain containing 5C; VPARP; VWA5C

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
143, 328417, 361046

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UKK3

Gene Symbols:
PARP4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PARP4 (NP_006428.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120489

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Antigen:
CHRM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHRM1

Gene Alias:
acetylcholine receptor; acetylcholine receptor, muscarinic 1; AChR M1; cholinergic receptor; cholinergic receptor muscarinic 1; Cholinergic receptor, muscarin 1; cholinergic receptor, muscarinic 1; cholinergic receptor, muscarinic 1, CNS; CHRM1; Chrm-1; HM1; M1; M1 mAChR; m1 muscarinic acetylcholine receptor protein; M1R; MGC30125; muscarinic acetylcholine receptor M1; muscarinic receptor M1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1128, 12669, 25229

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P08482, P11229, P12657

Gene Symbols:
CHRM1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CHRM1 (NP_0007292)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120490

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Antigen:
OCT1 (POU2F1)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POU2F1

Gene Alias:
2810482H01Rik; NF-A1; OCT1; oct-1; oct-1B; octamer binding protein 1; octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; Otf1; OTF-1; POU class 2 homeobox 1; POU domain, class 2, transcription factor 1; Pou2f1; ubiquitous transcription factor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171068, 18986

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P25425, P31503

Gene Symbols:
POU2F1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 15-290 of human POU2F1/OCT1 (NP_001185712.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG