PIPA5120587

Dynactin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5120587-Each-of-1 In Stock ₹ 43,079.46

PIPA5120587 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

Dynactin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DCTN1

Gene Alias

150 kDa dynein-associated polypeptide; AL022633; DAP 150; DAP150; DAP-150; DCTN 1; DCTN1; DP 150; DP150; DP-150; dynactin 1; dynactin 1 (p150, glued homolog, Drosophila); dynactin 1, retrograde axonal transport; dynactin subunit 1; Dynactin1; Glued; HMN7B; OTTHUMP00000202491; p135; p150; p150 glued; p150 glued homolog; p150<glued>; p150glued; p150-glued

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13191, 1639, 29167

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

3.35 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O08788, P28023, Q14203

Gene Symbols

DCTN1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 945-1139 of human DCTN1 (NP_001128513.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: U-251MG, HeLa, HepG2, 22RV1, Jurkat, Mouse testis, Rat testis
  • The target is usually found in the following locations: Cytoplasm, cytoskeleton
  • Immunogen sequence: PGLVKDSPLL LQQISAMRLH ISQLQHENSI LKGAQMKASL ASLPPLHVAK LSHEGPGSEL PAGALYRKTS QLLETLNQLS THTHVVDITR TSPAAKSPSA QLMEQVAQLK SLSDTVEKLK DEVLKETVSQ RPGATVPTDF ATFPSSAFLR AKEEQQDDTV YMGKVTFSCA AGFGQRHRLV LTQEQLHQLH SRLIS This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD
  • Dynactin binds to both microtubules and cytoplasmic dynein
  • Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis
  • This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus
  • Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms
  • Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).

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Img

Thermo Scientific

PIPA5120587

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Antigen:
Dynactin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCTN1

Gene Alias:
150 kDa dynein-associated polypeptide; AL022633; DAP 150; DAP150; DAP-150; DCTN 1; DCTN1; DP 150; DP150; DP-150; dynactin 1; dynactin 1 (p150, glued homolog, Drosophila); dynactin 1, retrograde axonal transport; dynactin subunit 1; Dynactin1; Glued; HMN7B; OTTHUMP00000202491; p135; p150; p150 glued; p150 glued homolog; p150<glued>; p150glued; p150-glued

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13191, 1639, 29167

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
3.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O08788, P28023, Q14203

Gene Symbols:
DCTN1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 945-1139 of human DCTN1 (NP_001128513.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120588

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Antigen:
ATP8B3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP8B3

Gene Alias:
aminophospholipid translocase ATP8B3; ATP1K; ATP8B3; ATPase class I type 8B member 3; ATPase phospholipid transporting 8B3; ATPase, aminophospholipid transporter, class I, type 8B, member 3; ATPase, class I, type 8B, member 3; ATPIK; FOS37502_2; Phospholipid-transporting ATPase IK; potential phospholipid-transporting ATPase IK; probable phospholipid-transporting ATPase IK

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
148229

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O60423

Gene Symbols:
ATP8B3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ATP8B3 (NP_620168.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120589

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Antigen:
APLF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APLF

Gene Alias:
2010301N04Rik; AI452191; APFL; APLF; aprataxin- and PNK-like factor; Aprataxin and PNK-like factor; aprataxin and PNKP like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; RGD1565557; XIP1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
500247

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
0

Gene Symbols:
APLF

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human APLF (NP_775816.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120596

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Antigen:
OSR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Osr1

Gene Alias:
ODD; Odd1; odd-skipped homolog; odd-skipped related 1; odd-skipped related 1 (Drosophila); odd-skipped related transciption factor 1; odd-skipped related transcription factor 1; Osr; OSR1; Protein odd-skipped-related 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
130497, 23967, 298878

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
B0K011, Q8TAX0, Q9WVG7

Gene Symbols:
Osr1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-115 of human OSR1 (NP_6603031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG