PIPA5120758

CD33 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120758-Each-of-1 In Stock ₹ 43,079.46

PIPA5120758 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

CD33

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD33

Gene Alias

CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12489, 690492, 945

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.09 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

P20138, Q63994

Gene Symbols

CD33

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human SIGLEC3/CD33 (NP_0017633)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: K-562, Mouse spleen, Mouse lung, Mouse brain, Rat lung
  • The target is usually found in the following locations: Cell membrane, Single-pass type I membrane protein
  • Immunogen sequence: YYDKNSPVHG YWFREGAIIS RDSPVATNKL DQEVQEETQG RFRLLGDPSR NNCSLSIVDA RRRDNGSYFF RMERGSTKYS YKSPQLSVHV TDLTHRPKIL IPGTLEPGHS KNLTCSVSWA CEQGTPPIFS WLSAAPTSLG PRTTHSSVLI ITPRPQDHGT NLTCQVKFAG AGVTTERTIQ LNVTYVPQNP TTGIFPGDGS GKQETRAGVV H CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family
  • It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface
  • CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia
  • Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells
  • CD33 is also expressed on, and is a useful marker for, peripheral monocytes
  • CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias
  • Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.

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Antigen:
CD33

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD33

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12489, 690492, 945

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.09 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P20138, Q63994

Gene Symbols:
CD33

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human SIGLEC3/CD33 (NP_0017633)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Antigen:
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Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Gene Alias:
CoV; S1; SARS; Spike

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
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Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
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Gene Symbols:
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Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of coronavirus Spike S1 (NP_8288511)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
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Isotype:
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Antigen:
SARS Coronavirus Spike Protein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
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Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.04 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Primary or Secondary:
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Antigen:
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Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Gene Alias:
CoV; RBD; SARS; Spike

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
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Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.15 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
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Gene Symbols:
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Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of coronavirus Spike RBD (NP_8288511)

Quantity:
100 μL

Primary or Secondary:
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Target Species:
Virus

Product Type:
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Isotype:
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