PIPA5120769

HCoV-HKU1 Spike S2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5120769-Each-of-1 In Stock ₹ 43,079.46

PIPA5120769 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

HCoV-HKU1 Spike S2

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

Coronavirus; HCoV; HKU1; S2; Spike

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 800-900 of coronavirus Spike S2 (YP_1732381)

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.75 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECDHis Tag)
  • Immunogen sequence: IVGQEEFIQT NSPKVTIDCS LFVCSNYAAC HDLLSEYGTF CDNINSILDE VNGLLDTTQL HVADTLMQGV TLSSNLNTNL HFDVDNINFK SLVGCLGPHC G The S2 Spike protein mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein
  • Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state
  • During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain
  • The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes
  • [Uniprot]

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Thermo Scientific

PIPA5120769

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Antigen:
HCoV-HKU1 Spike S2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Coronavirus; HCoV; HKU1; S2; Spike

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of coronavirus Spike S2 (YP_1732381)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120770

--


Antigen:
HCoV-OC43 Spike S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Coronavirus; HCoV; OC43; S1; Spike

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 97-196 of coronavirus Spike S1 (YP_0095552411)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.78 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120771

--


Antigen:
HCoV-OC43 Spike S2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Coronavirus; HCoV; OC43; S2; Spike

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 782-881 of coronavirus Spike S2 (YP_0095552411)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.95 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120772

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Antigen:
IKK alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human IKK alpha (NP_0012693)

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
2.08 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG