PIPA5120842

DUT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120842-Each-of-1 In Stock ₹ 43,079.46

PIPA5120842 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

DUT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dut

Gene Alias

5031412I06Rik; 5133400F09Rik; D2Bwg0749e; Deoxyuridine 5'-triphosphate nucleotidohydrolase; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; deoxyuridine triphosphatase; Dut; Dutp; dUTP diphosphatase; dUTP nucleotidohydrolase; dUTP pyrophosphatase; dUTPase; FLJ20622; PIP4; PPAR-interacting protein 4

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

110074, 1854, 497778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.94 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P33316, P70583

Gene Symbols

Dut

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 89-252 of human DUT (NP_001020419.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: LO2, Jurkat, HeLa
  • The target is usually found in the following locations: Mitochondrion, Nucleus
  • Immunogen sequence: PAPGPETPAI SPSKRARPAE VGGMQLRFAR LSEHATAPTR GSARAAGYDL YSAYDYTIPP MEKAVVKTDI QIALPSGCYG RVAPRSGLAA KHFIDVGAGV IDEDYRGNVG VVLFNFGKEK FEVKKGDRIA QLICERIFYP EIEEVQALDD TERGSGGFGS TGKN This gene encodes an essential enzyme of nucleotide metabolism
  • The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate
  • This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP
  • Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase
  • This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death
  • Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus
  • A related pseudogene is located on chromosome 19.

Compare Similar Items

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Img

Thermo Scientific

PIPA5120842

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Antigen:
DUT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dut

Gene Alias:
5031412I06Rik; 5133400F09Rik; D2Bwg0749e; Deoxyuridine 5'-triphosphate nucleotidohydrolase; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; deoxyuridine triphosphatase; Dut; Dutp; dUTP diphosphatase; dUTP nucleotidohydrolase; dUTP pyrophosphatase; dUTPase; FLJ20622; PIP4; PPAR-interacting protein 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110074, 1854, 497778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.94 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P33316, P70583

Gene Symbols:
Dut

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 89-252 of human DUT (NP_001020419.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120843

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Antigen:
mGluR8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRM8

Gene Alias:
A230002O04; FLJ41058; G protein coupled receptor, family C, group 1, member H; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H; GLUR8; glutamate metabotropic receptor 8; glutamate receptor; glutamate receptor, metabotropic 8; Gprc1h; Grm8; M mGlu8; Metabotropic glutamate receptor 8; metabotropic glutamate receptor subtype 8b; MGC126724; mGlu8; mGlur; mGluR8; mGluR8b

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2918

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.64 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O00222

Gene Symbols:
GRM8

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRM8 (NP_0008362)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120845

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Antigen:
MCT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC16A7

Gene Alias:
4921534N07Rik; MCT 2; Mct2; monocarboxylate transporter; Monocarboxylate transporter 2; Slc16a7; solute carrier family 16 (monocarboxylate transporter), member 7; solute carrier family 16 (monocarboxylic acid transporters), member 7; solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29735, 9194

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O60669, Q63344

Gene Symbols:
SLC16A7

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_0012575511)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120847

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Antigen:
MMP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP10

Gene Alias:
AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117061, 17384, 4319

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O55123, P07152, P09238

Gene Symbols:
MMP10

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_0024161)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG