PIPA5120943

Bestrophin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5120943-Each-of-1 In Stock ₹ 43,079.46

PIPA5120943 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

Bestrophin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BEST1

Gene Alias

ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24115, 7439

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.27 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O76090, O88870

Gene Symbols

BEST1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 376-585 of human BEST1 (NP_0041741)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: THP-1, BT-474, HeLa, Mouse heart, Mouse lung
  • The target is usually found in the following locations: Basolateral cell membrane, Cell membrane, Multi-pass membrane protein
  • Immunogen sequence: QPNQEDEEDA HAGIIGRFLG LQSHDHHPPR ANSRTKLLWP KRESLLHEGL PKNHKAAKQN VRGQEDNKAW KLKAVDAFKS APLYQRPGYY SAPQTPLSPT PMFFPLEPSA PSKLHSVTGI DTKDKSLKTV SSGAKKSFEL LSESDGALME HPEVSQVRRK TVEFNLTDMP EIPENHLKEP LEQSPTNIHT TLKDHMDPYW ALENRDEAHS The retinal pigment epithelium (RPE) and choroid represent a differentiated system of the eye that sustains normal retinal health and function
  • Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision
  • The lipofuscin-like material in the macular area appears as a yellow mass like the yolk of an egg that later becomes darker and irregular in color, a process known as &quotescrambling the egg&quote
  • Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells
  • Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium
  • Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current
  • The human Bestrophin gene encodes a 585 amino acid protein.

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Show Difference

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Thermo Scientific

PIPA5120943

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Antigen:
Bestrophin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BEST1

Gene Alias:
ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24115, 7439

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O76090, O88870

Gene Symbols:
BEST1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 376-585 of human BEST1 (NP_0041741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5120950

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Antigen:
Gemin 3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ddx20

Gene Alias:
component of gems 3; DDX 20; DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DEAD/H BOX 20; DEAD-box helicase 20; DEAD-box protein DP103; DKFZP434H052; DP 103; Dp103; GEMIN3; Gemin-3; I79_021005; probable ATP-dependent RNA helicase DDX20; putative ATP-dependent RNA helicase DDX20; regulator of steroidogenic factor 1; ROSF-1; SMN-interacting protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11218, 53975, 84473

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.05 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9JJY4, Q9UHI6

Gene Symbols:
Ddx20

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human DDX20 (NP_009135.4).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5120952

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Antigen:
MYST2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kat7

Gene Alias:
EC 2.3.1.48; HBO1; HBOa; histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K (lysine) acetyltransferase 7; K(lysine) acetyltransferase 7; Kat7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST protein 2; MYST2; MYST-2; ZC2HC7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11143, 217127, 303470

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O95251, Q5SVQ0, Q810T5

Gene Symbols:
Kat7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-193 of human KAT7 (NP_008998.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5120956

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Antigen:
PHC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PHC1

Gene Alias:
AW557034; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); early development regulatory protein 1; Edr; Edr1; hPH1; MCPH11; Mph1; PH1; Phc1; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); polyhomeotic-like protein 1; RAE28; RAE-28

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13619, 1911, 312690

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P78364, Q64028

Gene Symbols:
PHC1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 750-940 of human PHC1 (NP_004417.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG