PIPA5121149

AES Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121149-Each-of-1 In Stock ₹ 43,079.46

PIPA5121149 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

AES

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AES

Gene Alias

Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14797, 166

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

8.47 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P63002, Q08117

Gene Symbols

AES, TLE5

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human AES (NP_945320.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: A-549, HeLa, U-251MG, Mouse liver
  • The target is usually found in the following locations: Nucleus
  • Immunogen sequence: MCHKNGFPQE GGITAAFLQK RKLRLSKNHR PARAKVTEHV RGTRPGRATA GPAASTRAAG SLFFDRWGNR GPAGCRGSSH LPQQLKFTTS DSCDRIKDEF QLLQAQYHSL KLECDKLASE KSEMQRHYVM YYEMSYGLNI EMHKQAEIVK RLNGICAQVL PYLSQEHQQQ VLGAIERAKQ VTAPELNSII RQQLQAHQLS QLQALALPLT PLPVGLQPPS LPAVSAGTGL LSLSALGSQA HLSKEDKNGH DGDTHQEDDG EKSD Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
  • Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
  • Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
  • AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
  • It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
  • Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5121149

--


Antigen:
AES

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AES

Gene Alias:
Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14797, 166

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
8.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P63002, Q08117

Gene Symbols:
AES, TLE5

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human AES (NP_945320.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121150

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Antigen:
CHD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHD1

Gene Alias:
4930525N21Rik; AI851787; ATP-dependent helicase CHD1; AW555109; Chd1; Chd-1; chromodomain helicase DNA binding protein 1; chromodomain-helicase-DNA-binding protein 1; DKFZp686E2337; EC 3.6.1; EC 3.6.4.12; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1105, 12648, 308215

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.39 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14646, P40201

Gene Symbols:
CHD1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1600 to the C-terminus of human CHD1 (NP_001261.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121151

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Antigen:
eIF2b alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF2B1

Gene Alias:
26kDa; D5Ertd406e; eIF-2a; EIF2B; eIF-2B GDP-GTP exchange factor subunit alpha; Eif2b1; EIF2BA; eIF-2Balpha; eukaryotic translation initiation factor 2B subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 (alpha); eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa); eukaryotic translation initiation factor 2B, subunit 1 alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; GTP-exchange protein; translation initiation factor eIF-2B subunit alpha

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1967, 209354

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.89 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q14232, Q99LC8

Gene Symbols:
EIF2B1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human EIF2B1 (NP_001405.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5121154

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Antigen:
PFKP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PFKP

Gene Alias:
1200015H23Rik; 6-phosphofructo-1-kinase, C-type; 6-phosphofructokinase type C; 6-phosphofructokinase, platelet type; 9330125N24Rik; ATP:D-fructose 6-phosphate 1-phosphotransferase; ATP-dependent 6-phosphofructokinase, platelet type; ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; EC 2.7.1.11; HAMAP-Rule:MF_03184}; K6PP; PFK 1; PFK1; Pfkc; PFK-C; PFKF; PFKP; PFK-P; Phosphofructo-1-kinase isozyme C; Phosphofructokinase; phosphofructokinase 1; phosphofructokinase, platelet; Phosphofructokinase, platelet type; phosphohexokinase; phosphohexokinase {ECO:0000255

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5214, 56421, 60416

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P47860, Q01813, Q9WUA3

Gene Symbols:
PFKP

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 336-540 of human PFKP (NP_002618.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG