PIPA5121226

SPT5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5121226-Each-of-1 In Stock ₹ 43,079.46

PIPA5121226 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

SPT5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SUPT5H

Gene Alias

AL033283; AL033321; AU019549; DRB sensitivity-inducing factor 160 kDa subunit; DRB sensitivity-inducing factor large subunit; DSIF large subunit; DSIF p160; etID10129.15; etID37101.15; fb37g01; fb95e05; fog; foggy; hSPT5; protein foggy; Spt5; SPT5 homolog, DSIF elongation factor subunit; SPT5H; suppressor of Ty 5; suppressor of Ty 5 homolog; suppressor of Ty 5 homolog (S. cerevisiae); Supt5; Supt5h; supt5h protein; Tat-cotransactivator 1 protein; Tat-CT1; Tat-CT1 protein; Transcription elongation factor SPT5; transcription elongation regulator FOGGY; wu:fb37g01; wu:fb95e05; wu:fc10f02

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20924, 6829

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

2.27 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O00267, O55201

Gene Symbols

Supt5, SUPT5H

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 125-425 of human SUPT5H/SPT5 (NP_003160.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Positive test controls include: U-87MG, HeLa, A-549, Mouse liver
  • The target is usually found in the following locations: Nucleus
  • Immunogen sequence: LQNLWRDQRE EELGEYYMKK YAKSSVGETV YGGSDELSDD ITQQQLLPGV KDPNLWTVKC KIGEERATAI SLMRKFIAYQ FTDTPLQIKS VVAPEHVKGY IYVEAYKQTH VKQAIEGVGN LRLGYWNQQM VPIKEMTDVL KVVKEVANLK PKSWVRLKRG IYKDDIAQVD YVEPSQNTIS LKMIPRIDYD RIKARMSLKD WFAKRKKFKR PPQRLFDAEK IRSLGGDVAS DGDFLIFEGN RYSRKGFLFK SFAMSAVITE GVKPTLSELE KFEDQPEGID LEVVTESTGK EREHNFQPGD N Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II
  • DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A
  • DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter
  • Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex
  • DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II
  • TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme
  • Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites
  • DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat
  • DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA5121226

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Antigen:
SPT5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT5H

Gene Alias:
AL033283; AL033321; AU019549; DRB sensitivity-inducing factor 160 kDa subunit; DRB sensitivity-inducing factor large subunit; DSIF large subunit; DSIF p160; etID10129.15; etID37101.15; fb37g01; fb95e05; fog; foggy; hSPT5; protein foggy; Spt5; SPT5 homolog, DSIF elongation factor subunit; SPT5H; suppressor of Ty 5; suppressor of Ty 5 homolog; suppressor of Ty 5 homolog (S. cerevisiae); Supt5; Supt5h; supt5h protein; Tat-cotransactivator 1 protein; Tat-CT1; Tat-CT1 protein; Transcription elongation factor SPT5; transcription elongation regulator FOGGY; wu:fb37g01; wu:fb95e05; wu:fc10f02

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20924, 6829

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
2.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O00267, O55201

Gene Symbols:
Supt5, SUPT5H

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 125-425 of human SUPT5H/SPT5 (NP_003160.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121229

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Antigen:
Coronin 1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CORO1A

Gene Alias:
actin-binding; bovine p57; Clabp; Clabp coronin; CLIPINA; Clipin-A; CORO1; CORO1A; CORO1A protein; coronin 1; coronin 1A; coronin, actin binding protein 1A; coronin, actin binding protein, 1A; coronin-1; coronin-1A; coronin-like actin binding protein; coronin-like protein A; Coronin-like protein p57; FLJ41407; HCORO1; IMD8; Lmb3; MGC117380; p57; TACO; tryptophan aspartate-containing coat protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11151, 12721, 155151

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.83 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O89053, P31146, Q91ZN1

Gene Symbols:
CORO1A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-461 of human CORO1A (NP_001180262.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121230

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Antigen:
EGFL7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFL7

Gene Alias:
Cbl20; EGF like domain multiple 7; EGFL7; EGF-like domain 7; EGF-like domain-containing protein 7; EGF-like protein 7; EGF-like-domain, multiple 7; Epidermal growth factor-like protein 7; Estrogen-regulated protein CBL20 20.4kD; Estrogen-regulated protein CBL20, 20.4kD; Megf7; multiple EGF-like domain protein 7; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domain protein 7; multiple epidermal growth factor-like domains protein 7; NEU1; NEU1 protein; NOTCH4-like protein; RP11-251M1.2; UNQ187/PRO1449; Vascular endothelial statin; vascular endothelial-statin; VE-STATIN; Zneu1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
245963, 353156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.88 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q6AZ60, Q9QXT5

Gene Symbols:
EGFL7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-100 of human EGFL7 (NP_958854.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121231

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Antigen:
PYGM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYGM

Gene Alias:
AI115133; glycogen muscle; glycogen phosphorylase; glycogen phosphorylase, muscle associated; glycogen phosphorylase, muscle form; GPMM; muscle (McArdle syndrome); muscle glycogen phosphorylase; Muscpho; Myophosphorylase; PG; Phosphorylase glycogen; phosphorylase, glycogen, muscle; Phosphorylase, glycogen; muscle (McArdle syndrome); Pygm; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19309, 24701, 5837

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P09812, P11217, Q9WUB3

Gene Symbols:
PYGM

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 743-842 of human PYGM (NP_0056001)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG