PIPA5121234
PHLPP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121234-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5121234 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
PHLPP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PHLPP1
Gene Alias
AI836256, Circadian Oscillatory Protein (SCOP), EC 3.1.3.16, hSCOP, KIAA0606, mKIAA0606, PH domain and leucine rich repeat protein phosphatase 1, PH domain leucine-rich repeat protein phosphatase 1, PH domain leucine-rich repeat-containing protein phosphatase 1, PH domain-containing family E member 1, Phlpp, PHLPP1, pleckstrin homology domain containing, family E (with leucine rich repeats) member 1, pleckstrin homology domain-containing family E member 1, pleckstrin homology domain-containing family E protein 1, Plekhe1, PPM3A, protein phosphatase, Mg2+/Mn2+ dependent 3A, SCN circadian oscillatory protein, SCOP, Suprachiasmatic nucleus circadian oscillatory protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23239, 59265, 98432
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.94 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O60346, Q8CHE4, Q9WTR8
Gene Symbols
PHLPP1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1428 of human PHLPP1 (NP_919431.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Positive test controls include: HeLa, SH-SY5Y, Mouse testis, Mouse brain, Rat testis, Rat brain
- The target is usually found in the following locations: Cell membrane, Cytoplasm, Membrane, Nucleus, Peripheral membrane protein
- Immunogen sequence: DQPSTGDASG APAVWSHGYT EASGVKNKLC VAALSVNNFC DNREALYGVF DGDRNVEVPY LLQCTMSDIL AEELQKTKNE EEYMVNTFIV MQRKLGTAGQ KLGGAAVLCH IKHDPVDPGG SFTLTSANVG KCQTVLCRNG KPLPLSRSYI MSCEEELKRI KQHKAIITED GKVNGVTEST RILGYTFLHP SVVPRPHVQS VLLTPQDEFF ILGSKGLWDS LSVEEAVEAV RNVPDALAAA KKLCTLAQSY GCHDSISAVV VQLSVTEDS PHLPP1 is a member of the serine/threonine phosphatase family, which are important regulators of Akt serine-threonine kinases (AKT1, AKT2, AKT3) and conventional/novel protein kinase C (PKC) isoforms
- PHLPP1 and PHLPP2 have a similar domain structure and have been shown to dephosphorylate and inactivate, distinct Akt isoforms, at one of the two critical phosphorylation sites required for activation: Serine473
- PHLPP2 dephosphorylates AKT1 and AKT3, whereas PHLPP1 is specific for AKT2 and AKT3
- PHLPP1 promotes apoptosis and may act as a tumor suppressor
- Increased expression of PHLPP1 may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Compare Similar Items
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Antigen: PHLPP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PHLPP1
Gene Alias: AI836256, Circadian Oscillatory Protein (SCOP), EC 3.1.3.16, hSCOP, KIAA0606, mKIAA0606, PH domain and leucine rich repeat protein phosphatase 1, PH domain leucine-rich repeat protein phosphatase 1, PH domain leucine-rich repeat-containing protein phosphatase 1, PH domain-containing family E member 1, Phlpp, PHLPP1, pleckstrin homology domain containing, family E (with leucine rich repeats) member 1, pleckstrin homology domain-containing family E member 1, pleckstrin homology domain-containing family E protein 1, Plekhe1, PPM3A, protein phosphatase, Mg2+/Mn2+ dependent 3A, SCN circadian oscillatory protein, SCOP, Suprachiasmatic nucleus circadian oscillatory protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23239, 59265, 98432
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.94 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: O60346, Q8CHE4, Q9WTR8
Gene Symbols: PHLPP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1428 of human PHLPP1 (NP_919431.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PHLPP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PHLPP1
Gene Alias:
AI836256, Circadian Oscillatory Protein (SCOP), EC 3.1.3.16, hSCOP, KIAA0606, mKIAA0606, PH domain and leucine rich repeat protein phosphatase 1, PH domain leucine-rich repeat protein phosphatase 1, PH domain leucine-rich repeat-containing protein phosphatase 1, PH domain-containing family E member 1, Phlpp, PHLPP1, pleckstrin homology domain containing, family E (with leucine rich repeats) member 1, pleckstrin homology domain-containing family E member 1, pleckstrin homology domain-containing family E protein 1, Plekhe1, PPM3A, protein phosphatase, Mg2+/Mn2+ dependent 3A, SCN circadian oscillatory protein, SCOP, Suprachiasmatic nucleus circadian oscillatory protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23239, 59265, 98432
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.94 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
O60346, Q8CHE4, Q9WTR8
Gene Symbols:
PHLPP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1428 of human PHLPP1 (NP_919431.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MEPE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MEPE
Gene Alias: Matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein with ASARM motif (bone); matrix, extracellular phosphoglycoprotein with ASARM motif (bone); Mepe; OF45; osteoblast/osteocyte factor 45; Osteoregulin
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56955, 79110, 94111
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.91 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: Q8K4L6, Q9NQ76
Gene Symbols: MEPE
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MEPE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MEPE
Gene Alias:
Matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein with ASARM motif (bone); matrix, extracellular phosphoglycoprotein with ASARM motif (bone); Mepe; OF45; osteoblast/osteocyte factor 45; Osteoregulin
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56955, 79110, 94111
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.91 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
Q8K4L6, Q9NQ76
Gene Symbols:
MEPE
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FER
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FER
Gene Alias: AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14158, 2241, 301737
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.73 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P09760, P16591, P70451
Gene Symbols: FER
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human FER (NP_005237.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FER
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FER
Gene Alias:
AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14158, 2241, 301737
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.73 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P09760, P16591, P70451
Gene Symbols:
FER
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human FER (NP_005237.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Desmoglein 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DSG1
Gene Alias: Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1828, 291755
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.67 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q02413
Gene Symbols: DSG1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Desmoglein 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DSG1
Gene Alias:
Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1828, 291755
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.67 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q02413
Gene Symbols:
DSG1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG